Derm & ID Flashcards
Bowen’s Disese
SCC in situ
What is the first line antibiotic for skin infections?
Flucloxacillin (500 mg PO 6 hourly for 7 days)
What are the most common causative organisms of cellulitis (in immunocompetent pts)?
Streptococci (b haemolytic)
Staphylococci aureus
What cellulitis-causing organisms are immunocompromised patients at risk of catching?
P aeruginosa
C neoformans
P multicida
Outline the 4 main stages of HIV seroconversion (HINT: think “4 Fs”)
Flu-like illness - acute infection and propagation of virus in CD4+ and dendritic cells
Feeling fine - immune response is “successful” therefore the virus is quiescent (i.e. chronic latent infection)
Falling WCC - onset of AIDS due to failing of immune system
Final crisis - fatal AIDS-defining illness (opportunistic infection)
What are the CD4 counts of HIV patients during the chronic latent phase of infection (“feeling fine”)?
CD4 > 400
What CD4 count is diagnostic of AIDS?
CD4 < 200
List the (infective) causes of bloody diarrhoea (HINT: think CHESS)
Campylobacter Histolytica E. coli (O157) Shigella Salmonella
Does psoriasis affect mainly flexors or extensors?
Extensors
Does eczema affect mainly flexors or extensors?
Flexors
List the nails signs found with psoriasis
Discolouration
Pitting
Onycholysis
Subungual hyperkeratosis
List the drugs known to cause erythema multiforme / SJS / TEN (HINT: think SNAPP)
Sulphonamides NSAIDs Allopurinol Penicillin Phenytoin
What is the difference between bullous pemphigoid and pemphigus vulgaris?
Bullous pemphigoid - abs against hemidesmosomes causing tense bulae in the elderly
Pemphigus vulgaris - abs against desmosomes causing large, flaccid bullae that rupture easily in the young
Give examples of drugs along the steroid ladder
Class 4 - mild: hydrocortisone
Class 3 - moderate: eumovate
Class 2 - potent: betnovate
Class 1 - super-potent: demovate
