Derm (Alice) (15%) Flashcards
4 types of acne vulgaris
comedonal
papular
pustular
nodulocystic
blackheads are _ comedomes
whiteheads are _ comedomes
blackheads: open
whiteheads: closed
what type of acne is this
comedomal
what type of acne is this
papular
moderate number of lesions, little scarring
what type of acne is this
pustular
> 25 lesions
moderate scarring
what type of acne is this
nodulocystic
severe scarring
mc tx for acne
topical retinoids
tx for cystic acne
- tetracyclines
- oral retinoids - isotretinoin
s.e of isotretinoin
dry lips
liver damage
increased TG/cholesterol
pregnancy category X
birth control protocol for pt on isotretinoin
2 pregnancy tests prior to starting
montly pregnancy test while on in
gradual conversion of terminal hairs to indeterminate hairs to vellus hairs
aka male pattern baldness
androgenetic alopecia
mc age for androgenetic hair loss, men vs women
men: 20-40 yo
women: after 50 yo
bx findings of androgenetic hair loss
telogen and atrophic follicles
3 hormones associated w. androgenetic hair loss
testosterone
DHEA
prolactin
3 treatable causes of androgenetic hair loss
thyroid dysfunction
anemia
autoimmune
tx for androgenetic hair loss
topical minoxidil/rogaine
finasteride
spironolactone
pt ed for topical minoxidil/rogaine
hair loss before first regrowth
moa for finasteride
blocks T and DHT
moa for spironolactone
blocks DHT
pruritic, eczematous lesions, xerosis, and lichenification
atopic dermatitis
mc location of atopic dermatitis, infant vs adolescent
infant: face, scalp
adolescent: flexural surfaces
atopic dermatitis is a type _ hypersensitivity
1
management of atopic dermatitis (3)
clinical dx
patch testing to verify
allergy referral
tx for atopic dermatitis
- review meds/possible allergens
- antihistamines
- topical vs oral steroids
- PUVA phototherapy
3 mcc of burns
scalding
direct thermal
flame
range of depth of burns
superficial partial thickness
deep partial thickess
full thickness
characteristics of acid burns
coagulation
necrosis
eschar
characteristics of alklaline burns
liquefaction necrosis
deep damage
degrees of burns
1st (sunburn): skin blanches with pressure;
tender
2nd degree (partial thickness): skin red and blistered; tender
3rd degree (full thickness): skin tough/leathery; nontender
4th degree: into bone/muscle
what degree burn is this
2nd
what degree burn is this
third
what degree burn is this
4th
rule of 9’s for pediatric burns
head: 18%
each arm: 9%
chest: 18%
back: 18%
each leg: 14%
palmar method for pediatric burns
patient’s palm = 1%
used for small burns
tx for mild burns
ABCs
fluids
sulfadiazine
tx for mod/severe burns
cover with a dry dressing
admit
indications for fluids w. burns; children vs adults
children: > 10% BSA
adults: > 15% BSA
fluid protocol for burns: children vs adults
children: LR 3 ml/kg x %BSA
adults: LR 4 ml/kg x %BSA
half over the first 8 hr, half over 16 hr
bright pink, itchy rash with a linear pattern
+/- clear vesicles w.in
contact dermatitis
acute vs chronic contact dermatitis
acute: erythema, vesicles, bullae, burning, itching
chronic: scaling, lichenification, fissure - well demarcated border
allergic etiologies of contact dermatitis
nickel
poison ivy
allergic dermatitis is a type _ hypersensitivity
IV
irritant causes of contact dermatitis
cleaners
solvents
detergents
urine
feces
direct toxic effect of offending agent
pharm for contact dermatitis (5)
hydroxyzine vs benadryl
zinc oxide
triamcinolone vs oral steroids
burow’s solution
PUVA phototherapy
zinc oxide is commonly used for
diaper rash
elevated, erythematous rash with satellite pustules
diaper rash
3 secondary infxns associated w. diaper rash
candidiasis
impetigo
HSV
satellite lesions w. diaper rash make you think of what pathogen
candidiasis
mcc pathogen associated w. impetigo
s. aureus
what type of dermatitis makes you concerned about child sexual abuse
HSV
you should always check for _ on a child w. diaper rash
thrush
what is spared in perioral dermatitis
vermillion border (lip margin)
tx for perioral dermatitis
- topical metro vs erythromycin vs clindamycin
- topical pimecrolimus
- oral doxy
mc type of adverse drug rxn
skin
4 meds associated w. drug eruptions
PCNs
bactrim
NSAIDs
anticonvulsants
tx for anaphylaxis by pediatric weights
< 7.5 kg (16 lb): weight based; 0.15 mg of 1 mg/mL solution if no weight available
7.5 kg - 25 kg (16-55 lb): 0.15 mg autoinjector of 1 mg/mL solution
> 50 kg (110 lb): 0.5 mg of 1 mg/mL solution
tx for DIHS (drug induced hypersensitivity syndrome)
systemic steroids: 1 mg/kg/day
slow taper over 6 weeks
tx for uticaria
2nd gen antihistamines (ex zyrtec)
non itchy, maculopapular rash
3 areas of concentricity which are red/white/purple
target lesions
erythema multiforme
erythema multiforme is a type _ hypersensitivity
IV
erythema multiforme mc occurs on the (3)
hands
feet
mucosa
mcc of erythema multiforme (3)
pror infxn:
HSV
mycoplasma pna
URI
3 drugs that can cause erythema multiforme
sulfonamides
b lactams
phenytoin
2 hallmark characteristics of erythema multiforme
blanching
lack of itchiness
classification of erythema multiforme
minor: limited region, one type of mucosa
major: widespread, 2+ mucosa
erythema mc affects what mucosa
oral
what are these
target lesions -> erythema multiforme
multiple rings w. dusky center
major differentiation btw erythema multiforme and SJS/TEN
no nikolsky sign w. erythema multiforme
management of erythema multiforme (4)
throat swoothie/magic swizzle
severe: systemic steroids
occular: emergent ophtho consult
recurrent: antiviral qd
exanthems to know (5)
erythema infectiosum (5th disease)
hand-food-mouth dz
measles (rubeola)
rubella (german measles)
roseola (sixth disease)
slapped cheek rash
lacy/reticular rash on extremities
erythema infectiosum (5th disease)
erythema infectiosum (parvovirus) mc affects the _
and spares the _
affects: extremeties
spares: palms, soles
management of parvovirus (3)
supportive
anti-inflammatories
resovles in 2-3 weeks
hand-foot-mouth dz is caused by what pathogen in kids < 10 yo
coxsackievirus type A
management of hand/food/mouth dz
supprotive
anti-inflammatories
resolves in 10 days
what are the 4 c’s of measles (rubeola)
cough
coryza
conjunctivitis
cephalocaudal spread
what is this rash
brick red rash -> measles
what are these
koplik spots -> measles
red spots in buccal mucosa w. blue-white pale center
management of measles
supportive
antinflammatories
isolate for 1 weeks after onset of rash
MMR vaccine
3 day rash that first appears on the face, spreads caudally to the trunk and extremities, and becomes generalized w.in 24 hr
rubella (german measles)
differentiating factor btw rubeola and rubella
w. rubella:
rapid spread
rash does not darken or coalesce
serious complication of rubella
teratogenic in 1st trimester:
deafness
cataracts
TTP
mental retardation
management of rubella
supportive
MMR vaccine
only childhood exanthem that starts on the trunk and spreads to the face
HSV 6 or 7
-rose pink maculopapular blanchable rash on trunk/back and face
-preceded by high fever
roseola (sixth disease)
management of roseola
antipyretics
supportive
impetigo is mc caused by
- s. aureus
- GAS
impetigo mc occurs on the (2)
face
extremities
describe rash w. impetigo
red sores around nose/mouth that rupture, ooze, and form yellow-brown crust
mc type of impetigo
non bullous
bullae w. a varnish-like crust
fever, diarrhea
bullous impetigo
management of impetigo
- warm water soaks q 15-20 min
- topical mupirocin x 5 days
- widespread or bullous: oral keflex vs erythromycin
- MRSA: doxy
- sick + MRSA: vanco
complication of impetigo
post streptococcal glomerulonephritis
small white specs on the hair shaft
lice
management of lice
launder potential fomites
permethrin
-chronic, autoimmune, papulosquamous inflammatory dermatosis
-purplish, itchy flat-topped bumps on mucous membranes that form lacy white patches
lichen planus
5 p’s of lichen planus
purple
papule
polygonal
pruritis
planar
what is this showing
lichen planus
what is this showing
whitish lines in the papules of lichen planus -> wickham striae
tx for lichen planus
topical steroids
what is this showing
pityriasis rosea
-oval patch w. central clearing followed by diffuse diffuse papulosquamous rash
-lesions along langer lines
-christmas tree pattern
pityriasis rosea
management of pityriasis rosea
self limiting
topical vs oral steroids
antihistamines
asymptomatic = no tx
what is this showing
interdigital rash -> scabies
describe rash associated w. scabies (4)
severely pruritic papules
s-shaped linear burrows
in web spaces of hands, wrist, waist
worse at night
dx for scabies
skin scrape microscopy
tx for scabies
-topical permethrin to entire body - repeat in 1 week
-sulfur ointment if < 2 yo
-severe: oral ivermectin
contraindication for oral ivermectin
pregnant/bf’ing
pt ed for scabies
pruritis may persist 2-4 weeks after tx
SJS affects _% of the body
TEN affects _% of the body
SJS: < 10%
TEN: > 30%
management of SJS/TEN (4)
early admit to burn unit
ABC
fluids/lytes/nutrition
IVIG
what med used to be used for SJS/TEN but is now thought to increase risk of sepsis
steroids
3 rf for superficial fungal infxns
increased skin moisture
immunodeficiency
PVD
what is this showing
branching fungal hyphae w. septations ->
dermatophytes
budding yeast
pseudohyphae
candidiasis
short hyphae and clusters of spores
tinea versicolor
what is this showing
spaghetti and meatballs -> tinea versicolor
dermatophyte (tinea) infxns to know (7)
barbae
pedis
unguium (onychomycosis)
cruris
capitis
corporis (ringworm)
versicolor
tx for tinea barbae
oral antifungals:
griseofulvin microsize
vs
terbinafine
what dermatophyte is mc associated w. tinea pedis
trichophyton rubrum
tx for tinea pedis
topical antifungals
what dermatophyte is associated w. tinea unguium
onychomycosis
tx for tinea unguium
terbinafine
tx for finea cruris
topical antifungals
what pharm is NOT effective for tinea infxns
nystatin
mc fungal infxn in peds
tinea capitis
first line tx for tinea capitis
oral griseofulvin
which tinea do you think of when you see wrestlers
corporis (ringworm)
think close physical contact
tx for tinea corporis
topical antifungals
what dermatophyte causes tinea veriscolor
malassezia furfur
describe the tinea versicolor rash
hypo or hyperpigmented macules that do not tan
tx for tinea versicolor
selenium sulfide 2.5% applied to the skin for 10 min
then wash off thorouthly
blanchable, edematous, pink, papules and wheels or plaques on the surface of the skin
uticaria (hives)
what is darier’s sign
localized uticaria appearing where the skin is rubbed -> uticaria
darier’s sign is caused by
histamine release
painless, deeper form of uticaria affecting the lips, tongue, eyelids, hands, and genitals
angioedema
what is this showing
angioedema
tx for angioedema
- second gen antihistamines (H1 blockers -> zyrtec, allegra, claritin etc)
- first gen antihistamines if sleep disturbance (hydroxyzine, diphenhydramine)
- H2 blockers - cimetidine, ranitidine
- steroids
peds dosing for epinephrine
0.01 mg/kg SC/IV
flesh colored, sharply demarcated, rough, round, firm nodules
verruca - warts
all warts are caused by
HPV
5 types of warts
verruca vulgaris - common
verruca plana - flat
verrucae plantaris - plantar
condyloma acuminatum - venereal
epidermodysplasia verrucoformis: chronic, lifelong HPV
management of warts (3)
most self resolve w.in 2 years
cryotherapy
topical salycilic acid