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SKIN/MS FINAL > DERM > Flashcards

DERM Flashcards

1
Q

flat, circumsized region of skin w/different color or texture

A

macule

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2
Q

large macuole

A

patch

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3
Q

can feel, look abnormal, example is acne

A

papule

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4
Q

larger lesions of papules

A

plaques

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5
Q

clear fluid filled lesion-blister

A

vesicle

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6
Q

definition of neoplasia

A

uncontrolled cell growth

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7
Q

neoplasm w/no capability for metastasis

A

benign

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8
Q

has the potential for metastasis

A

malignant

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9
Q

malignant neoplasm

A

cancer

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10
Q

what is classified by the presence or absence of invasion past basement membrane into foreign tissue

A

epithelial neoplasm

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11
Q

what does IN SITU mean

A

benign (still located within the epidermis)

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12
Q

name of benign melanocytic neoplasm

A

nevi

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13
Q

benign neoplasms of melanocytes that everyone has

A

common/junction acquired or congenital

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14
Q

acquired nevi that starts within the epidermis

A

junctional

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15
Q

acquired nevi that starts within Dermal

A

compound

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16
Q

congenital nevus

A

very large, especially in kids

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17
Q

benign nevus that must always be cut off since some melanomas can resemble, red dome shaped commonly on cheak of child

A

spitz

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18
Q

starts in the dermis and can be commonly mistaken for melanoma (papule and dark)

A

blue nevus/dermal melanocytoses

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19
Q

clinically concerning nevi that has immune reaction so there’s white around mole

A

halo

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20
Q

dysplastic nevi

A

risk marker for melanoma - tends to be familial inherited

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21
Q

ABCD

A

asymmetry

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22
Q

Epithelial neoplasms

A

seborrheci keratosis

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23
Q

very common, and can develop into benign squamous epithelium. All is in the epidermis. Most people who have them have a ton.

A

Actinic keratosis

24
Q

scaly red papule that’s raised. Sun related.

A

Squamous cell carcinoma

25
Q

SCCIS

A

benign- contained in basement membrane

26
Q

SCC

A

malignant- invades basement membrane and dermis

27
Q

Can you shave squamous cell carcinoma

A

yes, depth doesn’t matter as much

28
Q

most common human malignancy that is slow growing. can rarely metastasize. Present w/pearly papule.

A

basal cell carcinoma

29
Q

type of epithelial neoplasm that can differentiate toward hair follicles, eccrine, sebaceous, or apocrine glands

A

adnexal

30
Q

syndrome that has multiple trichilemmonas (face), visceral carcinomas, cerebral lesions, macrocephaly

A

Cowden syndrome

31
Q

mutation that causes cowden syndrome

A

PTEN (tumor suppressor gene)

32
Q

Muir torre syndrome has…

A

mutations in DNA mismatch repair proteins

33
Q

how does muir torre syndrome manifest

A

sebaceous neoplasms

34
Q

T/F. You can shave sebaceous proliferations.

A

False, you must get to the deeper part of the lesion.

35
Q

rare, very aggressive epithelial cancer that has poor prognosis

A

merkel cell carcinoma

36
Q

what causes merkel cell carcinoma

A

polyomavirus

37
Q

stromal neoplasms

A

dermatofibroma

38
Q

common in younger women, has tan/brown papule on legs, do pinch test

A

Dermatofibroma

39
Q

how do you biopsy dermatofibromas?

A

deep shave underneath - you can’t just knick the top

40
Q

DFSP - dermatofibrosarcoma protuberans

A

poorly defined plaque on the buttox of lower legs

41
Q

proliferation of blood vessel in the dermis neoplasm, benign

A

Hemangioma

42
Q

common in kids and pregnant women but can be shaved off

A

pyogenic granuloma

43
Q

malignant vascular neoplasm caused by virus

A

kaposi sarcoma

44
Q

what virus causes karposi sarcoma

A

human herpes virus 8

45
Q

how do you biopsy karposi sarcoma

A

punch - need deeper

46
Q

bad, malignant vascular tumor that comes from sun damaged skin

A

angiosarcoma

47
Q

common benign peripheral nerve sheath tumor

A

neurofibroma

48
Q

where does cutaneous T cell lymphoma occur

A

non sun exposed areas (bathing suit distribution)

49
Q

where does the common type of T cell lymphoma occur…area of skin

A

epidermis (surface of skin)

50
Q

how does cutaneous B cell lymphoma present

A

single nodule on the head/face/neck

51
Q

where is cutaneous B cell lymphoma found?

A

deep dermis - punch biopsy is needed

52
Q

what is the best predictor for malignant melanoma

A

depth of invasion (breslow depth)

53
Q

what is used to measure breslow depth

A

millimeters

54
Q

what has a greater change of survival

A

less than 1.0 mm depth (stage 1)

55
Q

what can also be used to predict melanoma?

A

ulceration (ulcerated behave more poorly)

56
Q

do shave biopsies for..

A

most basal cells

57
Q

do punch biopsies for…

A

nodular basal cell carcinoma

SKIN/MS FINAL (6 decks)

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