Derm 4 - Inflammatory skin conditions Flashcards

1
Q

Which chronic inflammatory skin disorders follow a relapsing and remitting course?

A
  • Eczema
  • Psoriasis
  • Acne
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2
Q

What is the most common type of eczema?

A

Atopic eczema

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3
Q

Which chronic inflammatory skin condition is characterised by papule and vesicles on an erythematous base?

A

Atopic eczema

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4
Q

Name some triggers for atopic eczema:

A
  • Infection
  • Chemicals
  • Food
  • Dust
  • Pet fur
  • Sweating
  • Heat
  • Stress
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5
Q

What commonly presents as itchy, scaly dry erythematous patches, on flexor aspects of limbs?

A

Atopic eczema

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6
Q

Where does atopic eczema commonly affect the body in infants and adults?

A

Infants - Face and extensor aspects of limbs

Children/adults - Flexor aspects of limbs

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7
Q

Chronic scratching/ rubbing of atopic eczema can lead to what skin changes?

A

Excoriation

Lichenification

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8
Q

How would you treat mild atopic eczema?

A
  • Trigger avoidance
  • Freq emollients
  • Soap substitute
  • Topical hydrocortisone
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9
Q

How would you treat severe atopic eczema with secondary bacterial infections?

A
  • Trigger avoidance
  • Freq emollients
  • Soap substitute
  • Topical betamethasone
  • Flucloxacillin
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10
Q

Which topical immunomodulators can be used as steroid-sparing agents in atopic eczema?

A
  • Tacrolimus

- Pimecrolimus

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11
Q

What treatment can you try for severe non-responsive cases of atopic eczema?

A
  • Phototherapy

- Immunosuppressants: oral prednisolone, azathioprine, ciclosporin

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12
Q

Name the complication of atopic eczema caused by infection of herpes simplex virus:

A

Eczema herpeticum

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13
Q

What is the ladder of topical steroid therapy for atopic eczema?

A

Mild - hydrocortisone
Mod - Clobetasone
Potent - Betamethasone
V potent - Clobetasol

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14
Q

Name the inflammatory disease of pilosebaceous follicles:

A

Acne vulgaris

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15
Q

What is the cause of acne vulgaris?

A

Androgens

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16
Q

What kind of acne is described as non-inflammatory lesions with open and closed comedones?

A

Mild acne vulgaris

17
Q

What kind of acne is described as inflammatory lesions with papule, pustules, nodules and cysts?

A

Mod/severe acne vulgaris

18
Q

What are the topical therapies for acne vulgaris?

A
  • Benzoyl peroxide
  • Abx - Erythromycin
  • Retinoids - Tretinoin
19
Q

What are the oral therapies for acne vulgaris?

A
  • Abx - Tetracyline
  • Anti-androgens - Co-cyprindiol
  • Retinoids - Isotretinoin
20
Q

Name some complications of acne vulgaris:

A
  • Scarring
  • Hyperpigmentation
  • Deformity
  • Physiological and social effects
21
Q

What condition is benzoyl peroxide used in?

A

Acne vulgaris

22
Q

Which antibiotics are usually used for acne vulgaris?

A

Topical - Erythromycin

Oral - Tetracycline

23
Q

A chronic inflammatory skin condition due to hyperproliferation of keratinocytes and inflammatory cell infiltration…

A

Psoriasis

24
Q

Name the 6 types of psoriasis:

A
  • Plaque
  • Guttate
  • Sebhorrheic
  • Flexural
  • Pustular
  • Erythrodermic
25
Q

What is the most common type of psoriasis?

A

Chronic plaque psoriasis

26
Q

How does plaque psoriasis present?

A
  • Well-demarcated erythematous plaques with silvery scales
  • Itchy, burning, painful
  • Extensor surfaces (of children/adults)
27
Q

What nail changes are associated with psoriasis?

A
  • Oncholysis

- Nail pitting

28
Q

What are some features of psoriatic arthritis?

A
  • Joint pain and stiffness
  • Dactylitis
  • Spondylitis
  • Achilles tendonitis
  • Enthesitis
  • Uveitis
29
Q

List some topical therapies for psoriasis:

A
  • Emollients
  • Vitamin D analogues
  • Topical corticosteroids: hydrocortisone
  • Coal tar preparations
  • Dithranol
  • Topical retinoids: Tretinoin
  • Keratolytics: salicylic acid
  • Scalp preparations
30
Q

What treatments are available for extensive severe psoriasis?

A
  • Phototherapy
  • Oral immunomodulators: Methotrexate, ciclosporin, mycophenolate mofetil
  • Oral retinoids: Isotretinoin
  • Biologicals: Infliximab, Etanercept, Efalizumab
31
Q

What are the complications of psoriasis?

A
  • Erythoderma

- Psychological and social effects