Derm Flashcards
greater with pale skin
sun-exposed areas
Cutaneous Malignancies
Dx: biopsy
Tx: surgical removal
Flexor surfaces
Asthma, allergic rhinitis,
Atopic Dermatitis (Eczema)
Silvery, scaly plaques
Psoriasis
Herald patch spares palms and soles
looks like secondary syphilis
Pityriasis Rosea
Tx: UV light or steroids
Dandruff
Tx: steroids and antifungal agents
Seborrheic dermatitis
Pemphigus Vulgaris
Bullous Pemphigoid
Blistering Diseases
ABCDE
Malignant Melanoma
Diameter of >6 mm
Tx Malignant Melanoma
Full thickness biopsy
Pt. who had organ transplant and looks like a ulcer
Tx: biopsy and remove
Waxy, shiny like a pearl
Basal cell carcinoma
Tx for Basal cell Carcinoma
Mohs microsurgery
Most common skin cancer
Basal cell carcinoma
Reddish/purple spots
Kaposi sarcoma
Mediterranean and HIV
Virus with Kaposi sarcoma
HHV8
Kaposi Tx
treat the AIDS
Kaposi will resolve as CD4 increases
Vincristine or interferon
chemo if all else fails: liposomal doxorubicin
can progress to squamous cell carcinoma
Actinic keratoses
Tx for Actinic Keratosis
Curettage, cryotherapy, laser, topical 5-fluorouracil, imiquimod
Molluscum contagiosum Tx
Imiquimod
Stuck on appearance
liver spots
seborrheic keratoses
Seborrheic Keratoses Tx
cryotherapy
surgery
laser
removal is only for cosmetic reason
Eczema Tx
Topical corticosteroids Tacrolimus and pimecrolimus Antihistamines Antibiotics UV light
Tx Psoriasis
Local
Topical high potency steroids
Vitamin A and D
Coal Tar
Pimecrolimus and tacrolimus
Tx Psoriasis
Extensive
UV Light
TNF inhibitors
Methotrexate
Drugs that induce Pemphigus vulgaris
ACE I
Penicillamine
Phenobarbital
Penicillin
Biopsy shows autoantibodies on IF studies
Pemphigus vulgaris
Pemphigus Vulgaris Tx
Steroids
Azathioprine or mycophenolate
Rituximab or IVIG
Bullous pempigoid Tx
Prednisone
use azathioprine, cyclophosphamide, or mycophenolate to decrease steroid uses
Mild disease uses erythromycin, dapsone, nicotrinamide
Hx of those with Porphyria Cutanea Tarda
Liver disease Hepatitis C Alcoholism Estrogen use Iron overload
Porphyria Cutanea Tarda
Test
Increased uroporphyrins on 24 h urine
Def. of Uroporphyrin decaroxylase activity
Impetigo
Staph
look?
superficial bacterial skin infections
Tx Impetigo
Mild: Muciprocin, bacitracin, retapamulin
Severe: dicloxacillin or cephalosporin
MRSA: doxycyclin, clindamycin, TMP/SMX
Erysipelas
Strep
Look?
Bright, red, hot swollen
Lesion on face
Leukocytosis
Erysipelas/Cellulitis
Tx
Mild: oral: Dicloxacillin, cephalexin, cefadroxyl
Penicillin allergy: erythromycin, clarithromycin, clindamycin
Severe IV: oxacillin, nafcillin, cefazolin
Penicillin allergy: clindamycin, vancomycin
MRSA:Vancomycin, linezolid, daptomycin, tigecycline, cetaroline
Folliculitis/Furuncle/Carbuncle
Tx
Ox/Clox/Diclox/Naf
Penicillin Allergy mild rash
Tx with?
cephalosporin
Penicillin allergy
anaphylaxis
mild infection Tx with?
Macrolide, clindamycin, doxycycline, TMP/SMZ
Penicillin allergy anaphylaxis
severe infection Tx with?
vancomycin, linezolid, daptomycin, or tigecycline
Fungal infection topical antifungal
tx?
Clotrimazole, ketoconazole, econazole, miconazole, nystatin, ciclopirox
Fungal infection of hair and nails tx?
Terbinafine
itraconazole
Drugs that cause hypersensitivity reactions
Penicillin Sulfa drugs (thiazide, furosemide, sulfonylureas) Allopurinol Phenytoin Lamotrigine NSAID
drugs that cause hypersensitivity reactions also cause?
hemolysis
interstitial nephritis
thrombocytopenia
Morbiliform Rash
no mucous membrane involvement
No treatment
Erythema Multiforme
“target” lesions
mucous membrane not involved
from herpes or mycoplasma
tx: steroids might help
Stevens-Johnson Syndrome
Toxic Epidermal Necrolysis
Tx: IVIG
Staphylococcal Scalded skin syndrome
Toxic Shock Syndrome
TSS multiorgan involvement: hypotension, renal dysfunction, liver dysfunction, CNS involvement
SSSS and TSS
Tx?
Antistaph meds
oxacillin or nafcillin effective
cefazolin essentially equal