Derm Flashcards

1
Q

erythema multiforme looks like

A

target lesions with erythema

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2
Q

erythema multiforme associated with

A

HSV
drug eruptions
mycoplasma pneumoniae

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3
Q

herpangina

A

virus causing painful mouth blisters
common in kids
coxsackie & echovirus
resolves itself

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4
Q

orf

A

parapoxvirus
caused by handling infected sheep
firm, fleshy nodule on hand commonly that can be red/blue
-> pustule -> crust over
cllears itself in 3-6weeks

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5
Q

Primary syphilis infection

A

chancre (painless ulcer)
local non-tender lymphadenopathy

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6
Q

secondary syphilis infection

A

systemic symptoms: fevers, lymphadenopathy
rash on trunk, palms and soles
buccal ‘snail track’ ulcers (30%)
condylomata lata (painless, warty lesions on the genitalia )

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7
Q

tertiary syphilis infection

A

gummas (granulomatous lesions of the skin and bones)
ascending aortic aneurysms
general paralysis of the insane
tabes dorsalis
Argyll-Robertson pupil

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8
Q

Investigations for syphilis

A

bloods
swab chancre for PCR

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9
Q

treponoma pallidum

A

syphilis

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10
Q

borrelia burgdorferi

A

lyme disease

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11
Q

early + late signs lyme disease

A

early: erythema migrans
late: heart block, nerve palsies, arthritis

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12
Q

necrotising fasciitis types

A

type 1 is caused by mixed anaerobes and aerobes (often occurs post-surgery in diabetics). This is the most common type
type 2 is caused by Streptococcus pyogenes

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13
Q

tuberous sclerosis non-derm signs

A

epilepsy

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14
Q

tuberous sclerosis tumours

A

periungal fibromas
facial angiofibromas
hamartomas aka angiomyolipomas
bone cysts

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15
Q

tuberous sclerosis skin

A

ash-leaf macules
shagreen patches

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16
Q

erythema infectiosum

A

slapped cheek, parvovirus b19

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17
Q

investigation for parvovirus b19

A

antibody test for parvovirus b19 IgM

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18
Q

NF1 tumours & skin

A

cafe-au-lait macuels
neurofibromas
azillary or inguinal freckling
optic glioma
lisch nodules

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19
Q

NF1 non-derm sign

A

learning difficulty

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19
Q

superficial melanoma site

A

trunk and limbs

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20
Q

acral/mucosal lentiginous melanoma site

A

acral: soles of feet, hands and nailbeds

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21
Q

lentigo maligna melanoma sites

A

sun damaged face/scalp/neck

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22
Q

nodular melanoma sites

A

anywhere but often trunk

23
Q

most common sites for melanoma mets

A

lung
brain
liver

24
Q

melanoma types from most common to least

A

superficial spreading
nodular
lentigno maligna
acral

25
Q

major criteria melanoma

A

change in size
change in shape
change in colour

26
Q

Secondary features (minor criteria) melanoma

A

Secondary features (minor criteria)
Diameter >= 7mm
Inflammation
Oozing or bleeding
Altered sensation

27
Q

margins for excision if breslow thickness 0-1mm thick

A

1cm

28
Q

margins for excision if breslow thickness 1-2mm thick

A

1-2cm

29
Q

margins for excision if breslow thickness 2-4mm thick

A

2-3cm

30
Q

margins for excision if breslow thickness >4mm thick

A

3cm

31
Q

5 year melanoma survival if breslow thickness < 0.75 mm

A

95-100%

32
Q

5 year melanoma survival if breslow thickness >4mm

A

50%

33
Q

BCC what skin layer

A

keratinocytes in basal layer of epidermis

34
Q

SCC what skin layer

A

keratinocytes in suprabasal layers

35
Q

keratoacanthama looks like and may be confused with

A

looks like fast growing papule with keratin plug
may be confused with SCC

36
Q

Bowen’s disease

A

RED SCALY patches
often 10-15 mm in size
slow-growing
often occur on sun-exposed areas such as the head (e.g. temples) and neck, lower limbs

37
Q

Actinic keratosis

A

small, CRUSTY or scaly, lesions
may be pink, red, brown or the same colour as the skin
typically on sun-exposed areas e.g. temples of head
multiple lesions may be present

38
Q

SCC excision margins

A

if <20mm - excision margin 4mm
If >20mm - excision margin 6mm

39
Q

rodent ulcers

A

BCC

40
Q

Scabies treatment

A

permethrin 5% is first-line
malathion 0.5% is second-line
everyone in household
do full body TWICE, 7 days apart

41
Q

pompholyx

A

hands and feet
worse in sweaty and hot
small blisters
very itchy
management: emollients and topical steroids

42
Q

Dermatitis in acral, peri-orificial and perianal distribution

A

→ ?zinc deficiency

43
Q

SCC poorer prognosis if

A

diameter >20mm and depth >4mm

44
Q

high-risk patients and in cosmetically important sites treatment for scc?

A

Mohs

45
Q

SCC in situ AKA

A

Bowen’s disease

46
Q

SCC in situ AKA

A

Bowen’s disease

47
Q

Positive non-treponemal test + positive treponemal test
consistent with active syphilis infection

A

consistent with active syphilis infection

48
Q

Positive non-treponemal test + negative treponemal test

A

consistent with a false-positive syphilis result e.g. due to pregnancy or SLE

49
Q

Negative non-treponemal test + positive treponemal test

A

consistent with successfully treated syphilis

50
Q

RPR and VDRL are what type of syphilis tests

A

non-treponemal

51
Q

Syphilis management

A

IM Benzathine penicillin
OR doxy if pen allergic
then monitor non-treponemal levels: should decrease 4fold

52
Q

Fournier’s gangrene

A

nec fasc of the perineum

53
Q

which DM drug is most associated with fourniers gangrene

A

SGLT2 i

54
Q

pain, swelling, erythema at the affected site
often presents as rapidly worsening cellulitis with pain out of keeping with physical features
extremely tender over infected tissue with hypoaesthesia to light touch
skin necrosis and crepitus/gas gangrene are late signs

A

necrotising fasciitis