Cardiology Flashcards
STEMI
≥ 20 minutes symptoms AND persistent (> 20 minutes) ECG features in ≥ 2 contiguous leads of:
- 2.5 mm ST elevation in leads V2-3 in men under 40 years, or ≥ 2.0 mm ST elevation in leads V2-3 in men over 40 years
- 1.5 mm ST elevation in V2-3 in women
- 1 mm ST elevation in other leads
- new LBBB
Immeiate management STEMI
Give aspirin 300mg and determine PCI availability
PCI in STEMI
if present within 12 hours of the onset of symptoms AND PCI can be delivered within 120 minutes
Give prasugel
radial access is preferred to femoral access - give unfractionated heparin and bailout GPI
Fibronlysis in STEMI
within 12 hours symptom onset
give alteplase/
also give antithrombin
give ticagrelor after
if high bleeding risk in STEMI
give ticagrelor instead of prasugel in PCI
give clopidogrel instead of ticagrelor in fibrinolysis
If patient taking anticoagulants in STEMI
swap prasugel for clopidogrel
NSTEMI/unstable angina immediate management
aspirin 300mg
if no immediate PCI planned -> fondaparinux
estimate GRACE score
NSTEMI GRACE score <3%
give ticagrelor
if high bleeding risk -> give clopidogrel
NSTEMI GRACE score >3%
PCI immediately if clinically unstable
otherwise within 72hrs
give prasugrel (ticegralor if high bleeding risk)
give unfractionated heparin
ACEi C/I
pregnancy/breastfeeding
renovascular disease
aortic stenosis
K+ >5 ask a specialist
RF for infective endo
previous episode (strongest RF)
rheum. valve disease
prosthetic valve
congenital heart
IVDU
Most commonly affected heart valves in infective endocarditis
most common: MITRAL VALVE
IVDU: tricuspid
Native valve acute endocarditis most common cause
staph aureus
Most common endocarditis bug
staph aureus
Native valve subacute endocarditis bugs
strep viridans
enterococcus
Prosthetic valve endocarditis bugs
in first 2 months: staph epidermidis
after 2 months: staph aureus
MRSA
most common endocarditis bugs in IVDU
staph aureus