derm

Question 1

what is the most common cause of erythrodrma

Answer 1

atopic dermatitis exacerbation

Question 2

if a patient is started on lamotrigine and 2 months after develop target shaped lesions that start spreading everywhere what i the most likely diagnosis>?

Answer 2

steven johnson is a side effect tat typically starts 2 months after the start of the therapy

Question 3

what is the antibody present in CREST syndrome

Answer 3

anti centromere antibody in the central /limited scleroderma—calcinosis, raynaulds, esophageal dysmotility, sclerodectyle(skin of the palm really stiff causing the incurling of the finger) and telengectasia

Question 4

what is the pathophysiology of atopic eczema?

Answer 4

defect int he skin (fillagrin protein )

Question 5

what are the three skin manifestation if neurofibromatosis type 1?

Answer 5

cafe au lait spots, axillary freckling and lisch nodule of the eyes….complication - optic glioma Scoliosis and malformation of bones
Learning difficulties
Hypertension
Gastrointestinal bleeding/obstruction (due to tumours in the bowel)
Epilepsy (due to tumours in the brain)

Question 6

neurofibromatosis type 2 is associated with

Answer 6

bilateral vestibular schwanoma

Question 7

subepidermal split is seen in

Answer 7

bullous pemphigoid- seen in elderly

Question 8

what is the management of dermatitis herpetiformis ?

Answer 8

gluten free diet and dapsone (antibiotic) can help with the pruritus.

Question 9

what is the management of pyoderma gangrenosum?

Answer 9

topical or oral prednisolone is the first line other immunosuppressants are second line

Question 10

desquamation and Nikolsky sign is positive. There is marked crusting and fissuring around his mouth, although his oral mucosa is unaffected.

Answer 10

staphylococcus scalded skin syndrome….in TEN there will be mucosal involvement.
management is iv flucox or iv vanc

Question 11

what are the joints affected by psoriatic arthritis?

Answer 11

interphalangeal joint

Question 12

melanoma affecting face most commonly is

Answer 12

lentigo maligna mostly seen int he elderly individual, trunk-nodular and legs is superficial spreading

Question 13

what kind of rash is seen in a child if prescribed amoxicillin and he has infectitious mononucleosis

Answer 13

morbilliform rash… that is why in a sore throat phenoxymethylbenazine is preferred over amox

Question 14

longitudnal ridges are associated with which type of skin condition

Answer 14

lichen planus

Question 15

purplish rash around the eyes and gotron papule and myopathy are most likely associated with

Answer 15

dermatomyositis. diagnostic test is mucle biopsy.

Question 16

melanoma found on the sole of the foot or nail bed or palms are most commonly

Answer 16

acral lentiginous

Question 17

which condition causes a scarring alopecia with peri-follicular pustules and multiple hairs originating from a single follicle.

Answer 17

folliculitis decalvans….another cause of scarring alopecia is lichen planopilari

Question 18

what is the management of the infantile seborhhoic dermatitis

Answer 18

olive oil if not then topical antifungal ….in adults the first line is zinc-pyrithione

Question 19

what is the investigation you would do in a patient with bilateral purpuric rash , There is evidence of mild knee swelling bilaterally, and the abdomen is tender to mild palpation but is not peritonitis.

Answer 19

urine analysis for ig a nephropathy

Question 20

A 26-year-old woman presents to her GP with a scaly, mildly itchy, red rash over her face. She tells you it started when she was on her holiday in Greece two weeks ago but it is getting worse. She says it started as dark red firm areas of skin but there is now some white scaling areas too. On examination, there is a rash on her cheeks, scalp and bridge of nose. She also has some dull lesions over her face with lots of white scaling.

What is the most likely diagnosis?

Answer 20

discoid lupus erythamatous… seen in the sun exposed areas and more common in woman

Question 21

what is auspitz sign and which condition has it?

Answer 21

its seen in psoriasis where if you remove the plaque there will be pinpoint bleeding.

Question 22

which biopsy is suitable in a suspected melanoma?

Answer 22

excision

Question 23

maculopapular rash on the torso and palms and soles and lymphadenopathy is the most likely finding in (in a business man)

Answer 23

syphilis

Question 24

what are the 5 side effects of ciclosporins?

Answer 24

5hs- hypertrophy of gum, hypertension, hypertrichosis,hyperkalemia and hyperglycaemia

Question 25

what is the management of a melanoma if the breslow thickness is more than 1 mm

Answer 25

you have to take sentinal biopsy for metastasis to nodes

Question 26

what are the antibodies raised in dermatomyositis?

Answer 26

anti jo antibody