derm Flashcards
what is the most common cause of erythrodrma
atopic dermatitis exacerbation
if a patient is started on lamotrigine and 2 months after develop target shaped lesions that start spreading everywhere what i the most likely diagnosis>?
steven johnson is a side effect tat typically starts 2 months after the start of the therapy
what is the antibody present in CREST syndrome
anti centromere antibody in the central /limited scleroderma—calcinosis, raynaulds, esophageal dysmotility, sclerodectyle(skin of the palm really stiff causing the incurling of the finger) and telengectasia
what is the pathophysiology of atopic eczema?
defect int he skin (fillagrin protein )
what are the three skin manifestation if neurofibromatosis type 1?
cafe au lait spots, axillary freckling and lisch nodule of the eyes….complication - optic glioma Scoliosis and malformation of bones
Learning difficulties
Hypertension
Gastrointestinal bleeding/obstruction (due to tumours in the bowel)
Epilepsy (due to tumours in the brain)
neurofibromatosis type 2 is associated with
bilateral vestibular schwanoma
subepidermal split is seen in
bullous pemphigoid- seen in elderly
what is the management of dermatitis herpetiformis ?
gluten free diet and dapsone (antibiotic) can help with the pruritus.
what is the management of pyoderma gangrenosum?
topical or oral prednisolone is the first line other immunosuppressants are second line
desquamation and Nikolsky sign is positive. There is marked crusting and fissuring around his mouth, although his oral mucosa is unaffected.
staphylococcus scalded skin syndrome….in TEN there will be mucosal involvement.
management is iv flucox or iv vanc
what are the joints affected by psoriatic arthritis?
interphalangeal joint
melanoma affecting face most commonly is
lentigo maligna mostly seen int he elderly individual, trunk-nodular and legs is superficial spreading
what kind of rash is seen in a child if prescribed amoxicillin and he has infectitious mononucleosis
morbilliform rash… that is why in a sore throat phenoxymethylbenazine is preferred over amox
longitudnal ridges are associated with which type of skin condition
lichen planus
purplish rash around the eyes and gotron papule and myopathy are most likely associated with
dermatomyositis. diagnostic test is mucle biopsy.
melanoma found on the sole of the foot or nail bed or palms are most commonly
acral lentiginous
which condition causes a scarring alopecia with peri-follicular pustules and multiple hairs originating from a single follicle.
folliculitis decalvans….another cause of scarring alopecia is lichen planopilari
what is the management of the infantile seborhhoic dermatitis
olive oil if not then topical antifungal ….in adults the first line is zinc-pyrithione
what is the investigation you would do in a patient with bilateral purpuric rash , There is evidence of mild knee swelling bilaterally, and the abdomen is tender to mild palpation but is not peritonitis.
urine analysis for ig a nephropathy
A 26-year-old woman presents to her GP with a scaly, mildly itchy, red rash over her face. She tells you it started when she was on her holiday in Greece two weeks ago but it is getting worse. She says it started as dark red firm areas of skin but there is now some white scaling areas too. On examination, there is a rash on her cheeks, scalp and bridge of nose. She also has some dull lesions over her face with lots of white scaling.
What is the most likely diagnosis?
discoid lupus erythamatous… seen in the sun exposed areas and more common in woman
what is auspitz sign and which condition has it?
its seen in psoriasis where if you remove the plaque there will be pinpoint bleeding.
which biopsy is suitable in a suspected melanoma?
excision
maculopapular rash on the torso and palms and soles and lymphadenopathy is the most likely finding in (in a business man)
syphilis
what are the 5 side effects of ciclosporins?
5hs- hypertrophy of gum, hypertension, hypertrichosis,hyperkalemia and hyperglycaemia
what is the management of a melanoma if the breslow thickness is more than 1 mm
you have to take sentinal biopsy for metastasis to nodes
what are the antibodies raised in dermatomyositis?
anti jo antibody
