Depression & Antidepresseurs De Nouvelle Generation Flashcards

1
Q

Quand, en plus de la tristesse, les SX de la dépression sont une augmentation de affects négatifs(anxiété, peur, obsession/compulsion,culpabilité, irritabilité, colère) quel type d’agent prescrit-on?

A
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2
Q

Nommez quelques TCAs

A

Clomipramine
Protriptyline
Nortriptyline
Imipramine
Desipramine

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3
Q

Nommez quelques ISRS

A

Fluoxétine, citalopram escitalopram, paroxétine, sertraline

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4
Q

Effets secondaires ISRS ?

A

SNC: maux de tête, agitation, insomnie, tremblements fins
Cv: hypotension orthostatique, arythmie, tachycardie
GI/sex: inconfort abdominal, nausées
Dermato: urticaire, dermatite
Anticholinergique: constipation, bouche sèche

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5
Q

Contre-indication ISRS ?(2)

A
  1. Hypersensibilité connue à ces agents (réactions)
  2. Prise concomitante d’un IMAO (JAMAIS).
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6
Q

Nommez un ndri

A

Bupropion

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7
Q

Nommez 3 IRSN

A

Venlafaxine
Desvenlafaxine
Duloxetine

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8
Q

Nommez 1 SARI

A

Trazodone
Vilazodone
Vortloxetine

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9
Q

Nommez un nouvel AD approuvé au CAN

A

Mirtazapine
Agomelatine

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10
Q

Que signifie l’abréviation SARI?

A

Serotonin agonist and reuptake inhibitor

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11
Q

Quels sont les mécanismes d’actions des SARI?

A
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12
Q

Quels sont les mécanismes d’action de la mirtazapine?

A
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13
Q

Quels sont les symptômes d’arrêt pour les IMAO?

A
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14
Q

Quels sont les SX du syndrome d’arrêt des TCA?

A
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