Depression

Question 1

DSM 5 criteria to diagnose depression

Answer 1

5/9 or more FOR 2 WEEKS, must include **
MSIGECAPS
1. **Mood changes
2. Sleep changes
3. **Interest loss
4. Guilt, worthlessness
5. Energy loss
6. Concentration loss, indecisive
7. Appetite loss
8. Psychomotor changes
9. Suicidal

Question 2

PDD Persistant depressive disorder definition, also called as?

Answer 2

Dysthymia
Mild, prolonged depression for 2yrs

Question 3

Which c/f shows worst prognosis in MDD

Answer 3

Psychotic features
hallusinations etc

Question 4

C/F, Mx of depression in children

Answer 4

Irritability
Difficulty sleeping
Not enjoying meals
Low self esteem
low concentration

MX:
Fluoxamine»
Fluoxatime

Question 5

Recurrent brief depression, Mx

Answer 5

3-7 days episodes every month

Mx: CBT(Psychotherapy done by psychologist), Lithium

Question 6

Seasonal affective disorder

Answer 6

Winter blues
Mx: CBT, Phototherapy, SSRIs if necessary

Question 7

Mx of depression

Answer 7

Mild - CBt
Moderate - CBT +/- Antidepressants
Severe - CBT + Antidepressants, ECT(last resort)

SSRI takes 4-6wks for action
Continue for
1yr - first episode
2-3yrs - subsequent episodes

Question 8

Seretonin syndrome symptoms

Answer 8

Mental, Muscle (skeletal and smooth)
1. Mental/behaviour changes
Hypomania, seizures, agitation,confusion
2. Skeletal muscles (LL>UL)
Tremors, myoclonus, hyper-reflexia
3. Smooth muscles/autonomic function
Diarrhoea, fever, tachy,
Hyper/Hypotension

1. Diaphoresis (↑Sweating)
2. Mydriasis

Question 9

Drugs causing seretonin syndrome

Answer 9

Causing ↑Seretonin
1. Antidepressants
2. Selegiline
3. St Johns wort
4. Opioids (tramadol)
5. Lithium
6. Anti emetics
7. Illicit drugs

Question 10

Seretonin syndrome vs Neuroleptic malignant syndrome

Answer 10

SS:
1. Acute onset, Rapid recovery
2. Hyper-reflexia
3. Myoclonus, tremors
4. Pupils - dilated

NMS - caused d/t antipsychotics
1. Gradual onset, prolonged recovery
2. Hyporeflexia
3. Diffuse RIGIDITY
4. Pupils normal