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Y2 BRS Psychiatry > Depression > Flashcards

Depression Flashcards

1
Q

What is the monoamine deficiency hypothesis?

A

Depression is due to functional deficit of central monoamine transmission.

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2
Q

What central monoamine transmission is deficitent?

A

NA and 5-HT/serotonin

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3
Q

What is the functional deficit of central monoamine transmission called?

A

Monoamine deficiency hypothesis

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4
Q

What are the causes of depression?

A
  1. Cushing
  2. Hypothyroidism
  3. Anaemia
  4. Diabetes
  5. Personal factors (death/abuse)
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5
Q

What are the core symptoms of depression?

A
  1. Anergia
  2. Anhedonia
  3. Low mood
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6
Q

What is anergia?

A

Low energy

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7
Q

What is anhendonia?

A

Less pleasure in things you enjoyed

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8
Q

What are the biological symptoms of depression?

A
  1. Weight loss
  2. Low libdio
  3. Early morning awakening
  4. Sleep disturbance
  5. Psychomotor
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9
Q

What are the cognitive symptoms of depression?

A
  1. Reduced memory and concentration
  2. Guilt
  3. Low self esteem
  4. Bleak future
  5. Self harm
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10
Q

What are the signs of depression?

A
  1. Unkempt
  2. Poor eye contact
  3. Slow speech
  4. Good insight
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11
Q

How long do you have to have depression for a diagnosis?

A

Two weeks

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12
Q

What are the different severity levels of depression?

A
  1. Mild
  2. Moderate
  3. Severe
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13
Q

What do you need for a diagnosis of mild depression?

A

2 core symptoms and 2 additional symptoms

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14
Q

What do you need for a diagnosis of moderate depression?

A

2 core symptoms and 3 additional symptoms

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15
Q

What do you need for a diagnosis of severe depression?

A

2 core symptoms and 4 additional symptoms

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16
Q

What drugs can be used to treat depression?

A
  1. Tricyclic antidepressants
  2. MAO inhibitors
  3. Selective serotonin reuptake inhibitors
  4. ECT`
17
Q

What tricyclic antidepressant can be used to treat depression?

A

Amytriptyline

18
Q

What MAO inhibitor can be used to treat depression?

A

Phenelzine

19
Q

What selective serotonin reuptake inhibitor can be used to treat depression?

A

Fluoxetine

20
Q

What is the principle action of tricyclic antidepressants?

A

Block NA & 5-HT reuptake

21
Q

What is the principle action of MAO inhibitors?

A

Increases stores of NA & 5-HT

22
Q

What is the principle action of selective serotonin reuptake inhibitors?

A

Selective 5-HT2 reuptake inhibition

23
Q

What is the principle action of ECT?

A

Increases CNS responses to NA & 5-HT

24
Q

What effect on mood do tricyclic antidepressants have?

A

Increase mood

25
Q

What effect on mood do MAO inhibitors have?

A

Increase mood

26
Q

What effect on mood do selective serotonin reuptake inhibitors have?

A

Increase mood

27
Q

What effect on mood does ECT have?

A

Increase mood

28
Q

What does ECT stand for?

A

Electrochemical therapy

Y2 BRS Psychiatry (5 decks)

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