deposition, cysts Flashcards
amyloidosis
large mass eosinophilic hyaline material dermis subcutis
- Accentuated deposition around deep vascular channels and adnexal structures
- Plasma cells large russel bodies at margins within amyloid islands
- FB Giant cells ,focal calcifications
amyoloidosis stains
crystal violet/ thioflavin T
congo/pagoda/scarlet red
keratin stains in amyloidsis
EAB903, EKH4
amyloid organ involvement
kidney heart liver, lichenified skin( kc degeneration)
gout
- amorphous eosinophil deposits dermis/subcutaneous tissue
- brown doubly refractive needle shaped crystals in clefts
- lymphocytes histiocytes MNGC
gout stain
+ von kossa stain de galantha(urate specific)
pretibial myxedema
- large spaces w -abundant acid MPS btw collagen bundles
- normal/incr fibroblast/mast cells
digital myxoid cyst
- hyperplasia epidermis, epidermal collarette
- localised incr mucin clefts btw collegn bundles
- cystic space
- no epithelial lining
digital myxoid cyst stain
acid mucopolysaccharide stain
mucocele
ruptured minor salivary duct/gland
space filled sialomucin
lined-granulation/mixed- fibroblast lymph histio
sialomucin + MPS/Acid MPS
calcinosis cutis
dark basophilic brittle fractured deposits
surrounded by fibrosis/FB reaction
calcinosis cutis stains
von kossa,alizarin red
pilar cyst
cyst contains amorphous dense compact homogenised keratin
lined by squamous epithelium
pale keratinocytes no granular layer
calcification
dermoid cyst
cyst lamellated keratin, hair shafts
lined squamous epithelium with granular layer
multple hair follicles open with pilosebaceous units
dermoid cyst location
lateral eyebrow extend bone