deposition, cysts Flashcards

1
Q

amyloidosis

A

large mass eosinophilic hyaline material dermis subcutis

  • Accentuated deposition around deep vascular channels and adnexal structures
  • Plasma cells large russel bodies at margins within amyloid islands
  • FB Giant cells ,focal calcifications
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

amyoloidosis stains

A

crystal violet/ thioflavin T

congo/pagoda/scarlet red

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

keratin stains in amyloidsis

A

EAB903, EKH4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

amyloid organ involvement

A

kidney heart liver, lichenified skin( kc degeneration)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

gout

A
  • amorphous eosinophil deposits dermis/subcutaneous tissue
  • brown doubly refractive needle shaped crystals in clefts
  • lymphocytes histiocytes MNGC
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

gout stain

A

+ von kossa stain de galantha(urate specific)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

pretibial myxedema

A
  • large spaces w -abundant acid MPS btw collagen bundles

- normal/incr fibroblast/mast cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

digital myxoid cyst

A
  • hyperplasia epidermis, epidermal collarette
  • localised incr mucin clefts btw collegn bundles
  • cystic space
  • no epithelial lining
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

digital myxoid cyst stain

A

acid mucopolysaccharide stain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

mucocele

A

ruptured minor salivary duct/gland
space filled sialomucin
lined-granulation/mixed- fibroblast lymph histio
sialomucin + MPS/Acid MPS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

calcinosis cutis

A

dark basophilic brittle fractured deposits

surrounded by fibrosis/FB reaction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

calcinosis cutis stains

A

von kossa,alizarin red

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

pilar cyst

A

cyst contains amorphous dense compact homogenised keratin
lined by squamous epithelium
pale keratinocytes no granular layer
calcification

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

dermoid cyst

A

cyst lamellated keratin, hair shafts
lined squamous epithelium with granular layer
multple hair follicles open with pilosebaceous units

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

dermoid cyst location

A

lateral eyebrow extend bone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

vellus hair cyst

A

small cyst lammellated keratin vellus hair shafts
lined squamous epithelium granular layer
hair follicle attached to cyst

17
Q

steatocystoma

A
  • cyst sparse keratn, hair shafts/empty
  • cyst wall ruggated squamous epithelium
  • wrinkled crenulated eosinophilic refractile cuticle of keratin
  • sebaceous gland within cyst wall opening into cyst
18
Q

steatocystoma multiplex - multiple genetic cause

also found in>

A

k17

also in PC