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NBDE Pt. I > Dental Decks > Flashcards

Dental Decks Flashcards

1
Q

Organ undergoes regeneration:

A

Liver, bone, cartilage, intestinal mucosa; low-specialization

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2
Q

Composed of monocytes + macrophages

A

Reticuloendothelial system (AKA mononuclear phagocytic system) – in reticular connective tissue (spleen)

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3
Q

Microglia

A

Macrophages of CNS

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4
Q

Kupffer cells

A

Line blood vessels of liver

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5
Q

Alveolar macrophage

A

Dust cells; lining of lungs

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6
Q

Histiocytes

A

Macrophages in connective tissue

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7
Q

Gaucher’s disease

A

deficiency in glucocerebrosidase

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8
Q

Niemann-Pick disease

A

deficiency in sphingomyelinase

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9
Q

Tay-Sachs

A

deficiency in hexosaminidase A

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10
Q

Lipid Storages Diseases

A

Gauchers
Niemann-Pick
Tay-Sachs

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11
Q

Teratology

A

Study of developmental anomalies
Chemical, physical, biologic agents that cause developmental anomalies
Variable susceptibility, specific in each developmental stage and mechanism
Dose dependent
Produce death, growth retardation, malformation, or functional impairment
First trimester

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12
Q

Physical agents, teratogenic

A

Radiation
Hypoxia
Excessive carbon dioxide
Mechanical trauma

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13
Q

Maternal infection, teratogenic

A 
TORCH:
Toxoplasmosis
Other agents
Rubella
Cytomegalovirus
Herpes simplex
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14
Q

Hormones, teratogenic

A

Sex

Corticosteroids

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15
Q

Vitamin deficiencies, teratogenic

A

Riboflavin
Niacin
Folic acid
Vitamin E

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16
Q

Chemotherpay drugs, teratogenic

A

Treating malignancies

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17
Q

Antibiotics, teratogenic

A

Mitomycin
Dactinomycin
Puromycin

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18
Q

Delayed closure of two granulating surfaces is referred to as

A

Second intention

19
Q

First intention

A

Fibrous adhesion w/o supparation or granulation tissue formation

20
Q

Second intention

A

Connective tissue repair; large, exudative wound + netcrotic tissue, supparation, granulation

21
Q

Third intention

A

Filling via granulation and cicatrization

22
Q

Tissues taken from an individual of the same spcies who is NOT geneticaly related to the recipient is called an:

A

Allograft/homologous/homoplastic

23
Q

Xenograft

A

Another species, temporary, rejected – Hypersensitivity Type IV

24
Q

Autograft

A

Transplant of tissue from one part of body to another

25
Q

Isograft

A

From genetically idental species (twins)

26
Q

When a graft is rejected the first time, and tried again it will be rejected

A

MORE RAPIDLY

27
Q

According to the Spaulding Classification System for contaminated items and surfaces, critical items should be decontaminated after cleaning by

A

Sterilization and holding in sterilized state

28
Q

Spaulding Classification System

A

Critical = sterilization + holding in state
Vascular system, body tissues

Semi-Crit = High level disinfection (heat, chemicals)
Mucous membranes

Non-Crit = Intermediate/low level disinfection
Intact skin

29
Q

Bacteria notable for fluorescent pigments + their resistance to disinfectants & antibiotics:

A

Pseudomonas (i.e. Aeruginosa – toxic proteins, extensive tissue damage, interfere with immune defense)

Gram (-), straight/curved rod, obligate anaerobes

30
Q

P. aeruginosa

A

Exoenzyme S = impair phagocytic cells in blood stream + internal organs
Exotoxin A = inhibits protein synthesis

31
Q

Gentamicin

A

Aminoglycoside antibiotic, effective in treating bacteremias (P. aeruginosa)

32
Q

T-cell product stimulates growth of pluripotent hematopoietic stem cells

A

IL-3 (produced by leukocytes)

Regulate inflammatory + immune responses

33
Q

IL-1

A

Macrophages; Stimulation of T cells, antigen-presenting cells, B cell growth, antibody production, promotes hematopoiesis (blood cell formation)

34
Q

IL-2

A

Activated T-cells; proliferation of activated T-cells

35
Q

IL-3

A

T-lymphocytes; growth of blood cell precursors

36
Q

IL-4

A

T cells + mast cells; B cell proliferation, IgE production

37
Q

IL-5

A

T-cells + mat cells; Eosinophil growth

38
Q

IL-6

A

Activated T-cells; synergistic effects with IL-1 or TNF-alpha

39
Q

IL-7

A

Thymus + bone marrow stromal cells; development of T cell and B cell precursors

40
Q

Rubella Virus

A

Member of togavirus family, enveloped, (+) stranded, ss-RNA genome; German measles; teratogen; transmitted via respiratory droplets; prevention via live, attenuated vaccine; posterior auricular lymphadenopathy

41
Q

Hypersensitivity, Type I

A

Immediate; IgE Ab mediated-mast cell activation + degranulation “hay fever”, asthma, anaphylaxis

42
Q

Hypersensitivity, Type II

A

Cytotoxic; IgG, IgM Abs formed against cell surface antigens; complement involved; autoimmune hemolytic anemias, Ab-dependent cellular cytotoxicity (ADCC); Goodpasture disease

43
Q

Hypersensitivity, Type III

A

Immune complex disease; IgG, IgG, IgA against exo/endogenous antigens; complement + leukocytes (neutrophils, macrophages) involved; autoimmune diseases – SLE, rheumatoid arthritis, glomerulonephritis

44
Q

Hypersensitivity, Type IV

A

Mononuclear cells (T-lymphocytes, macrophages) w/ ILs and lymphokine production; contact, Tuberculin, granulomatous hypersensitivity

NBDE Pt. I (6 decks)

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