DENSITY AND SPECIFIC GRAVITY Flashcards
Mass per unit volume of a substance
Density
What is density expressed as
Grams per cubic centimeter
What is the density of water?
1g/cc
Formula of density
Density = Mass/Volume
Is a ratio, expressed decimally, of the weight of a substance to the weight of an equal volume of a subtance
Specific Gravity
The weight of a substance relative to the weight of a standard
Relative Value
Formula for Specific Gravity
Specific Gravity = Weight of substance/Weight of Equal Volume of Water
What substances are lighter than water?
A specific gravity of less than 1
What substances are heavier than water?
Specific gravity is greater than 1
Concrete number
Density
Units of measure varies
Density
Maybe expressed as
1g/mL, 1000g/L, 62.5 lb/cu ft
Abstract number
Specific Gravity
No unit
Specific gravity
Glass bottle to determine specific gravity
Pycnometer
What is the formula for calculating the weight if the volume and specific gravity is given
Grams = mL x specific gravity
What id the formula for calculating the volume if the weight and specific gravity is given
mL = Grams/Specific Gravity
Convert the weight of an ingredient or preparation to volume or vice versa
Pharmaceutical Applications of Specific Gravity
Calculate the equivalent strength of a preparation on the basis of either weight or volume
Pharmaceutical Applications of Specific Gravity
Preparation of total parenteral nutrition (TPN) admixtures
Pharmaceutical Applications of Specific Gravity
Specific gravity is an important factor for urinalysis
Clinical Application
What are the percentage strengths?
% w/v
% v/v
% w/w
Ratio Strength
5% into 1/20 or 1:20
1:20 into 5%
How to convert product percentage strength mg/ml?
Multiply the % strength expressed as a whole number by 10
Example: 4% x 10 = 40mg/mL
Expresses the number of mg of substance in 100 mL of liquid
Milligrams percent
It is used to occasionally to denote the concentration of a drug or natural substance in a biologic fluid, as in the blood.
Milligrams Percent
How are strengths pf very dilute solutions are commonly expressed?
Ppm or ppb
What are the methods to reduce or enlarge formulas
Ratio and Proportion
Dimensional Analysis
Factor Method: Simplest Method