Dengue Virus

Question 1

is a viral infection
transmitted to humans
through the bite of
infected mosquitoes?

Answer 1

Dengue

Question 2

A single positive-stranded RNA virus of the family
Flaviviridae; genus Flavivirus?

Answer 2

Dengue Virus

Question 3

Family of Dengue Virus?

Answer 3

Flaviviridae

Question 4

4 serotypes of Dengue?

Answer 4

DENV-1
DENV-2
DENV-3
DENV-4

Question 5

The primary vectors that transmit the disease are?

Answer 5

Aedes aegypti

Question 6

Life stages of mosquito?

Answer 6

Adult
Eggs
Larva
Pupa

Question 7

The Aedes mosquitoes breed in forested areas using tree holes as its
natural habitat, but nowadays it has well adapted to urban habitats
and breeds mostly in ______ including buckets, mud
pots, discarded containers and used tires, storm water drains etc.,
thus making dengue an insidious disease in densely populated urban
centers.

Answer 7

man-made containers

Question 8

Phases of dengue infection?

Answer 8

Febrile Phase
Critical Phase
Recovery Phase

Question 9

Fever usually lasts 2-7 days.
➢ Other signs and symptoms may include severe headache; retro-orbital eye
pain; muscle, joint, and bone pain; macular or maculopapular rash; and
minor hemorrhagic manifestations including nosebleed/epistaxis, bleeding
gums, or a positive tourniquet test result?

Answer 9

Febrile Phase

Question 10

Phase when patient can either improve or deteriorate?

Answer 10

Critical Phase

Question 11

Occurs between 3 to 7 days of illness?

Answer 11

Defervescence

Question 12

is known as the period in which the body temperature (fever) drops
to almost normal (between 37.5 to 38°C)?

Answer 12

Defervescence

Question 13

Those who will improve after defervescence will be ?categorized as

Answer 13

Dengue without Warning Signs

Question 14

While those who will deteriorate will
manifest warning signs and will be categorized as?

Answer 14

Dengue with
Warning Signs

Question 15

As plasma leakage subsides and hemodynamic status stabilizes,
patients’ general well-being improves?

Answer 15

Recovery Phase

Question 16

Laboratory Tests fo Dengue?

Answer 16

1. Dengue NS1 RDT
2. Dengue IgM/IgG
3. PCR
4. NAAT-LAMP
5. PRNT

Question 17

Requested between 1-5
days of illness. After day 7,
NS1 test is not
recommended?

Answer 17

Dengue NS1 RDT

Question 18

Requested beyond five days of
illness?

Answer 18

Dengue IgM/IgG

Question 19

One of the gold standard
laboratory tests to confirm
dengue virus?

Answer 19

PCR

Question 20

A novel molecular-based
confirmatory test used to detect
dengue virus?

Answer 20

NAAT - LAMP

Question 21

Gold standard to characterize
and quantify circulating level of
anti-DENV neutralizing antibody
(NAb)?

Answer 21

PRNT

Question 22

Other tests: routinely used in hospitals standard dengue diagnostic test?

Answer 22

-Total WBC Count
- Platelet
-Hematocrit

Question 23

decreasing WBC?

Answer 23

Leukopenia

Question 24

Decreasing platelet?

Answer 24

Thrombocytopenia

Question 25

Dengue symptoms usually last for?

Answer 25

2-7 Days

Question 26

Incubation period of dengue?

Answer 26

4-10 Days

Question 27

Dengue illness is categorized according to level of severity:

Answer 27

1. Dengue without warning signs 2. Dengue with warning signs 3. Severe dengue

Question 28

A previously well individual with acute febrile illness of 1- 7 days duration plus two of the following: headache, body malaise, retro-orbital pain, myalgia, arthralgia, anorexia, nausea, vomiting, diarrhea, flushed skin, rash (petechial, Hermann’s sign)?

Answer 28

Suspect dengue

Question 29

A suspect dengue case plus laboratory test: Dengue NS1 antigen test and at least CBC (leukopenia with or without thrombocytopenia) or dengue IgM antibody test (optional)?

Answer 29

Probable Dengue

Question 30

A suspect or probable dengue case with positive result of viral culture and/or Polymerase Chain Reaction (PCR) and/or Nucleic Acid Amplification Test- Loop Mediated Amplification Assay (NAAT-LAMP) and/ or Plaque Reduction Neutralization Test (PRNT)?

Answer 30

Confirmed dengue

Question 31

Q previously well person with acute febrile illness of 1- 7 days plus any of the following: abdominial pain or tenderness, persistent vomiting, clinical signs of fluid accumulation (ascites), mucosal bleeding, lethargy or restlessness, liver enlargement, increase in haematocrit and/or decreasing platelet count?

Answer 31

Dengue with warning signs

Question 32

Severe bleeding and plasma leakage leading to shock (DSS)-hypotension, weak pulse fluid accumulation with respiratory distress?

Answer 32

Severe Dengue

Question 33

Patients who may be sent home?

Answer 33

Group A

Question 34

Patient who should be referred for in hospital management?

Answer 34

Group B

Question 35

Patient with severe dengue requiring emergency treatment and urgent referral?

Answer 35

Group C

Question 36

Greeting the severity of thingy infection? Fever with two or more of the following: headache, retro-orbital pain, myalagia, arthralgia?

Answer 36

Grade 0

Question 37

Grading disability of dengue infection with positive tourniquet test?

Answer 37

Grade I

Question 38

Grading the severity of dengue infection with a spontaneous bleeding?

Answer 38

Grade II

Question 39

Grading the severity of thinking infection with circulatory failure?

Answer 39

Grade III

Question 40

Grading the severity of dengue infection with profound shock with undetectable blood pressure and pulse?

Answer 40

Grade IV