Demetia and Delirium Flashcards
Define cognitive impairment
A disturbance of higher cortical functions
What is meant by higher cortical functions?
Memory
Thinking
Judgement
Language
Perception
Awareness
How is cognitive impairment variable?
It can affect a single or multiple higher cortical functions.
It can be static or progressive.
Is cognitive impairment a specific illness?
No
If cognitive impairment is not a specific illness, what is it?
A description of someone’s condition
Define dementia
A persistent and disabling cognitive impairment with a decline in memory and thinking sufficient to impair personal ADL’s
What does ADL stand for?
Activities of daily living
What do patients with dementia have problem with?
Processing incoming information
What do patients with dementia have problem with as a result of not being able to process incoming information?
Maintaining and directing attention
What level of consciousness do people with dementia display?
Clear consciousness
How long must a person have these symptoms before being diagnosed with dementia?
6 months
What can often happen despite the commonness of dementia?
Missed diagnosis
Is dementia static or progressive?
Nearly always progressive
What is meant by ‘the inverse care law applies to dementia’?
Those who are most dependent and vulnerable often have the least awareness of their disability
What diseases can cause dementia?
Alzheimer’s disease
Vascular dementia
Frontotemporal dementia
Dementia with Lewy bodies
Huntington’s disease
Other causes
Describe the features of early stage dementia
Forgetfulness and other memory symptoms
Subtle changes in mood and behaviour, e.g. loss of motivation
Usually little intrusion into day to day activities if they are not too demanding
Describe the features if mid-stage dementia
More prominent memory problems
Difficulty with language and executive function may emerge
Marked changes in behaviour
More obvious disability
Complex events may be difficult to deal with e.g. managing finances
Usually require frequent support
Awareness of disability may start to diverge from reality
Describe the features of late stage dementia
Severe and pervasive memory problems
Severe disorientation and failure to recognise familiar people
Marked behavioural changes e.g. restlessness, disinhibition, severe apathy
Basic aspects of personal function begin to fail and generally require more or less continuous supervision
Describe the course and onset of Alzheimer’s
Gradual, insidious onset with slow progression
Describe the early symptoms of Alzheimer’s
Usually memory impairment
What neurological symptoms are associated with Alzheimer’s?
None
Describe the mood and behavioural changes that can accompany Alzheimer’s
May be minimal initially, but pre-existing anxiety may worsen
Describe the structural brain imaging seen in Alzheimer’s
Volume loss in the medial temporal lobe, posterior cingulate and precuneus
Describe the course and onset of vascular dementia
May be gradual or more abrupt onset
Erratic course
Describe the early symptoms seen in vascular dementia
Variable, but may be prominent dysexecutive features
What neurological features accompany vascular dementia?
Highly variable
What mood and behavioural changes may accompany vascular dementia?
Depression is common after a stroke
Emotional lability
What structural brain imaging changes are seen with vascular dementia?
May be evidence of infarcts, bleeds and white matter ischaemia
Describe the course and onset of frontotemporal dementia
Gradual onset but may progress quickly especially in younger patients
Describe the early symptoms seen in frontotemporal dementia
Loss of executive function and impaired social behaviours
What neurological features are seen with frontotemporal dementia?
Frontal release signs
What mood and behavioural changes may be seen in frontotemporal dementia?
Apathy
Loss of volition
Disinhibition
What changes in structural brain imaging can be seen with frontotemporal dementia?
Frontotemporal atrophy
Describe the course and onset of Lewy body dementia
Fluctuating episodic course
May initially look like delirium
What early symptoms may present in Lewy body dementia?
Perceptual disturbance (hallucinosis) and Parkinsonism