Dementia - Hon

Question 1

Criteria for diagnosis of Alzheimer’s

Answer 1

Deficits in 2 or more areas of cognition
Worsening of memory and other cognition
No consciousness issues
Onset usually after 65
Absence of other systemic or brain diseases

Question 2

Supporting findings for Alzheimer’s

Answer 2

Progressive cognitive functions…Aphasia, Apraxia, Agnosis
Impaired activities in daily living and behavioral changes
Family history
Normal L.P.
Normal EEG
Progressive atrophy on MRI or CT

Question 3

Memory deficits
Normal general cognition and daily activities
Pre-Alzheimer’s

Answer 3

Mild Cognitive Impairment

Question 4

Criteria for Vascular Dementia

Answer 4

Dementia (loss of 2 cognitive areas)
CV disease defined by focal neurologic findings
Evidence of relevant CV disease on brain imaging (infarcts)
Multiple basal ganglia/white matter lesions, etc.

Question 5

Rapidly-progressing Alzheimer’s symptoms
Parkinsonian symptoms
Psychotic symptoms
VERY sensitive (bad) to anti-psychotic agents

Answer 5

Diffuse Lewy Body Disease

Question 6

Alzheimer’s vs. Lewy Body Disease

Answer 6

LBD - more rapid progression, unexplained episodes of confusion and delirium (for days to weeks), Parkinsonian symptoms, psychotic, sensitive to anti-psychotic agents

Question 7

Loss of memory
Lack of spontaneity
Difficulty in thinking or concentrating
Speech disturbances
Emotional dullness
Loss of moral judgment
Progressive dementia
Fronto-temporal atrophy

Answer 7

Pick’s disease

Question 8

Dementia
Gait disturbance
Urinary incontinance

Answer 8

Normal Pressure Hydrocephalus