Delirium, sepsis Flashcards
what is delirium?
Delirium is a serious medical emergency and defined as a state of mental confusion or acute confusional state.
- A syndrome manifesting as an acute change in mental status that is characterised by inattention and disturbance in cognition that develops over a short period of time with a fluctuating course of symptoms.
- Medical emergency. Acute onset.
what are statistics of people that have delirium? relation to dementia>
- Can be difficult to distinguish dementia from delirium. Some may have both. If clinical uncertainty exists over the diagnosis, the person should be managed initially for delirium.
- 10% of nursing home residents have it
- 20% of people in hospital have it
- Associated with a 35-40% risk of death after it first presents
- 50% of over 65s in hospital will have had delirium at some stage
- Individuals who develop delirium are more likely to stay in hospital for longer, have dementia at a 3 year follow up, have more complications and require long term care.
Who is delirium most common to?
-More common in people with poor eyesight, poor hearing, dementia, constipation, patients who are frail, prescribed multiple medications, have pain, injury, infection etc
what is the difference between dementia and delirium?
Think: OCD CAMPS
Delirium VS Dementia
Rapid- hours to days [ ONSET] Insidious- months (+)
Fluctuating- “sundown” [COURSE] Progressive
Reversible- days- week [DURATION] Irreversible
Altered [CONSCIOUSNESS] often normal
signific inattention and no conc [ATTENTION] often normal
Immediate recall impaired [MEMORY] often normal
Hyper/hypoactive [PSYCHO MOTOR CHANGES] none
often reversed [SLEEP WAKE CYCLE] often normal
what is hypoactive delirium?
= reduced appetite, paucity of speech, with or without prompting, withdrawn, quiet and sleepy. Least likely to be detected by clinicians. It is also less studied, which effectively means there is less good quality evidence with regard to outcomes.
Hyperactive delirum?
= heightened arousal, restless, agitated and aggressive.
why is hypoactive delirium underdetected?
Because the patients do not present a management challenge. Often people will document ‘quiet day’ in the notes.
why is hyperactive delirium often detected quickly?
Because these patients are often more challenging and moving round the ward presenting a risk to themselves and others.
what are the symptoms of delirium?
- Fluctuation
- change in mood
- change in alertness
- agitation
- drowsiness
- hallucinations
- delusions
what are the risk factors for delirium?
- infection
- multiple medicines
- changed environment
- dehydration
- surgery
- constipation
- pain
- hearing impairment
what are the pre-disposing factors for delirium?
- Age- increases the risk
- Dementia or pre-existing cognitive impairment
- History of delirium
- People with dementia
- TIA’s or stroke
- Functional or sensory impairment
- Comorbidity or severity of illness
- Depression
- alcohol abuse
what are the precipitating factors for delirum?
- Major surgery (i.e hip surgery)
- Trauma or urgent admission to hospital
- Infecton
- Coma
- Polypharmacy
- Use of psychoactive or sedative-hypnotic drugs
- Any iatrogenic event
- Use of physical restraints
- Bladder catheterisation
- Physiological and metabolic abnormalities e.g high blood-urea nitrogen: creatinine ratio, abnormal sodium, glucose or potassium concentrations in serum hypoxaemia or metabolic acidosis.
assessment tools for delirium: 4AT
outline and give examples of what it can be used with?
-4AT
This a validated 2-minute tool for delirium detection.
Designed to help quickly and easily detect delirium in routine clinical practise.
No special training required.
All patients can be assessed, including those unable to speak (e.g with severe drowsiness)
Incorporates the Months Backwards test and the Abbreviated Mental test- 4 (AMT4), which are short tests for cognitive impairment.
Can be combined with single monitoring tool like the Single Question in Delirium (SQiD) or the NEWS2.
what are the 4 sections for 4AT?
Alertness: (high=4),
4 cognitive based question: age, DOB, location and current year.
(score 1= 1 wrong, 2+=2),
Attention: recite months of year backwards
(score 0.1 or 2),
Acute change of fluctuating course
Has there be an acute change in the person’s awareness, cognition or mental function which can include things like hallucinations, paranoia that’s been arising within the last 2 weeks, but is still evident the last 24hours.
This is hard to assess, because difficult to see if a person has a baseline cognitive impairment such as dementia.
Ideally, need collateral information from the family etc.
“Fluctuating” cognitive means to be coherent at one point and then not another. Score of 4 is given if patient has acute// fluctuating awareness etc.
If overall score is 4 or above= high chance for delirium then need to alert medical team.
1-3 at AMT= could be underlying cognitive impairment. May lead to referral to memory team for possible dementia etc
methods for measuring delirium: CAM
WHAT IS THIS ?
- Designed to allow non-psychiatric clinicians (with training ofc) to diagnose delirium quickly and accurately post formal cognitive testing.
- CAM diagnostic algorithm based on 4 cardinal features if delirium: 1) acute onset and fluctuating course, 2) inattention, 3) disorganized thinking, and 4)altered level of consciousness. A diagnosis according to the CAM requires the presence of features 1,2 and either 3 or 4.
- In critical care/recovery room after surgery, CAM-ICU should be used.