Delilrium Vs Dementia Flashcards
Delirium
Sudden, transient onset of clouded sensorium
Delirium Causes
Toxins Alcohol/drug abuse Trauma Impactions in the elderly Poor nutrition Electrolyte imbalances Anesthesia
Dementia
Gradual memory loss with decreased intellectual functioning usually occurring over the age of 60
Dementia Causes
Atherosclerosis Neurotransmitter Deficit Cortical atrophy Ventricular dilation Loss of brain cells Possible viral causes Alzheimer’s (most common)
Dementia Mneumonic to rule out other diseases
D= drug reaction/interactions E= Emotional disorders M= Metabolic/endocrine disorders E= eye and ear disorders N= Nutritional problems T= Tumors I = Infection A= Arteriosclerosis
Alzheimer’s Disease
The development of multiple cognitive defects characterized by both memory impairment and one or more of the following:
Aphasia
Apraxia
Agnosia
In ability to plan, organize, sequence and make abstract difference
Additional findings: Limb rigidity Flexion posture Disorientation Gait disturbances Impaired memory Other
Alzheimer’s Incidence/Causes
The most common cause of dementia
Unknown cars; affects over 5.8 million individuals in the United States; women greater than men
Earliest complaints from family: loss of short-term memory
Acetyl choline deficiency
Alzheimer’s Diagnostics
Usual lab diagnostics should be drawn to rule out other diseases: CBC, LYTES, Glucose, blood urea nitrogen, liver function tests, B12, been a real disease research laboratory
CT or MRI to rule out tumors
Alzheimer’s Management
Neurological consult
Cholinesterase inhibitors (increase the availability of acetylcholine):
donepezil (Aricept) (all stages)
galantamine (razadyne) (mild to mod)
Rivastigime (Exelon) (mild to mod)
N-methyl D- aspartate (NMDA)
Memantine (namenda) (Mod to severe)
Combination preparations:
Memantine and donepezil (Namzaric) (mod to severe)
Refer patient/family for counseling as appropriate