Definitions/Examination findings

Question 1

Chronic drainage of ears is an indicator of which immune dysfunction?

Answer 1

Antibody deficiency

Question 2

Oral candidiasis is indicative of which potential immunodeficiencies?

Answer 2

T cell or phagocyte deficiency

Question 3

Absent tonsillar tissue is indicative of which primary immunodeficiencies?

Answer 3

SCID

X-linked agammaglobulinemia

Question 4

What does PAMPS stand for?

Answer 4

pathogen associated molecular patterns

Question 5

What does the term class switching refer to?

Answer 5

isotype switching from IgM to IgG/IgA/IgE

Question 6

Hypocalcaemia, abnormal facies, heart disease in <6/12?

Answer 6

DiGeorge

Question 7

Delayed umbilical cord separation, leukocytosis, recurrent infections in <6/12?

Answer 7

Leukocyte adhesion deficiency type 1

Question 8

Diarrhoea, thrush, pneumonia, FTT, skin rash in <6/12?

Answer 8

SCID

Question 9

Male infant, mouth ulcers, neutropenia, recurrent infections in <6/12?

Answer 9

X-linked Hyper IgM

Question 10

Severe progressive infectious mononucleosis?

Answer 10

XL lymphoproliferative disorder

Question 11

Paralytic ileus following PO polio, no LN?

Answer 11

XLA (X-linked agammaglobulinemia)

Question 12

Recurrent cutaneous & systemic staph infections, coarse facial features (nose)?

Answer 12

Hyper IgE (Job’s syndrome)

Question 13

Sinopulmonary infections, neurological deterioration, telangiectasia?

Answer 13

Ataxia Telangiectasia

Question 14

Oculocutaneous albinism + recurrent infection?

Answer 14

Chediak Higashi

Question 15

Patient has severe reaction to blood products, associated with Crohns, Celiacs, UC?

Answer 15

IgA deficiency

Question 16

What is the most common primary immunodeficiency?

Answer 16

IgA deficiency

Question 17

Which primary immunodeficiency is a/w retention of primary teeth?

Answer 17

Hyper IgE syndrome