Definitions

Question 1

Define tolerance

Answer 1

When an individual needs to used an increased dose of a substance to feel the same effect.
Due to desensitisation of receptors or induction/inhibition of metabolic enzymes

Question 2

Define addiction

Answer 2

Chronic neurochemical relapse disorder, characterised by compulsion to take the drug, loss of control in limiting intake and emergence of a negative emotional state

Question 3

Define withdrawal

Answer 3

Symptoms experienced when the drug is not consumed.
Physical - shivering, joint aches, stomach cramps, sweating (take a couple of weeks to go)
Emotional - anxiety, low mood, craving, irritability (can persist for a year, is the main relapse trigger)