Definitions

Question 1

Definition: Acute liver failure

Answer 1

1. Severe liver injury
2. Altered mental status
3. Coagulopathy (INR>1.5)

in a patient WITHOUT preexisting liver disease

Question 2

Definition: AKI

Answer 2

1) Increase in serum creatinine by 0.3mg/dL or more within 48 hours OR
2) Increase in serum creatinine to 1.5x baseline or more within the last 7 days
OR
3) Urine output less than 0.5 mL/kg/h for 6 hours.