Deep vein thrombosis and pulmonary thromboembolism Flashcards
Symptoms/signs of DVT
Unilateral limb swelling
Persisting discomfort
Calf tenderness
(Warmth, redness - erythema)
Symptoms/signs of PE
Pleuritic chest pain Dyspnoea Haemoptysis Tachycardia Pleural rub on auscultation
Symptoms/signs of massive PE
Severe dyspnoea of sudden onset Collapse Blue lips and tongues = cyanosis Tachycardia Low BP Raised JVP Altered heart sounds May cause sudden death
Risk factors for venous thrombosis
Statis/hypercoagubility
- Increasing age
- Immobility
- Tissue trauma
- Obesity
- Pregnancy
- Exogenous oestrogen: oral contraceptive/HRT
- Smoking
- Some systemic diseases: cancer
- Inheritence
Risk of VTE in travel increased in:
Tall Short Overweight Women on the combined contraceptive pill Those in window seats
Investigations of DVT
Clinical assessment
Blood test: D-dimer
Imaging: compression US
Diagnosis of PE
Clinical assessment D-dimer Imaging - Isotope ventilation - Perfusion scan - CT pulmonary angiogram
Prevention of VTE in hospital
Early mobilisation
Anti-embolism stockings
Other physical methods
Daily injections of low molecular weight heparin
Indications for use of graduated compression stocking’s
Prevention of DVT Chronic venous insufficiency Varicose veins Oedema Lymphodema Prevention of post phlebeitc syndrome
Treatment of VTE
Principally low molecular weight heparin for 5 or more days, then oral anticoagulant (warfarin) for at least 3 months
Thrombolysis for massive PE
(Vena caval filter)