deck_5557422 Flashcards
How does diffusion distance affect the rate of simple diffusion?
The thicker the membrane across which molecules have to diffuse, the slower the rate of diffusion
How does surface area affect the rate of simple diffusion?
More diffusion can take place across a larger surface area. Cells specialised for absorption have extensions to their cell surface membranes called microvilli, which increase surface area
How does the size of the diffusing molecules affect the rate of simple diffusion?
Smaller ions or molecules diffuse more rapidly than larger molecules
How does the concentration gradient affect the rate of simple diffusion?
The steeper the gradient, the faster the diffusion to the side where there are fewer molecules, down the gradient
Small molecules that have polarity such as ions that have an electrical charge, are insoluble in lipid, why?
Because they can’t interact with the hydrophobic tails of the lipid bilayer, meaning they diffuse through water filled protein channels (pores) embedded in the membrane
What is the diameter around these channels?
0.8nm
How do cholesterol molecules within membranes affect the permeability of the membranes?
They reduce the permeability to small water-soluble molecules
Can glucose molecules diffuse through the water filled protein channel in membranes?
No, they are too large but they can bind to a transmembrane carrier protein which then opens to allow the glucose to pass out on the other side of the membrane. There are specific carrier proteins for different types of molecules
How to membranes differ in different cell types?
Different cell types have membranes with differing proportions of transmembrane protein channels and transmembrane protein carriers. This allows cells to control the types of molecules that pass in or out
What are neurone plasma membranes like?
They have many channels specific to either sodium or potassium ions. The diffusion of these ions into and out of the neurone axon is crucial for the conduction of nerve impulses. At synapses, there are also calcium ion channels and there may be chloride ion channels
What are the plasma membrane of epithelial cells that line airways like?
They have chloride ion channels and these play a crucial role in regulating the composition of mucus to trap particles and pathogens
What is the definition of osmosis?
The passage of water molecules down their water potential gradient, across a partially permeable membrane-It is the diffusion of water molecules
What is the definition of water potential?
The measure of the tendency of water molecules to diffuse from one region to another
What is a solvent?
In a solution, the liquid in which solute molecules are disolved
What is the solvent in an aqueous solution?
Water
What are the conditions like inside and outside of the cell?
Inside the cell is cytoplasm which contains water and the external medium is also watery as its surrounded by extracellular tissue fluid
Why do water molecules spread out?
Because they have kinetic energy and move about randomly
What is the process of osmosis?
The net diffusion from a region where there are relatively more water molecules to an area where there are fewer water molecules across a partially permeable membrane
What happens when solute molecules are added to water?
The relative number of water molecules, in the resulting solution, is changed
What happens if the solute molecules dissociate into charged ions such as sodium chloride dissociating into sodium and chloride ions?
They exert more effect on the relative number of water molecules than larger, non polar molecules such as glucose, because the number of particles in the solution doubles
What is water potential?
A measure of the tendency of water molecules to diffuse from one region to another