deck_551928

Question 1

Give five causes of acute inflammation

Answer 1

• Microbial infections e.g. pyogenic organisms * Hypersensitivity reactions * Physical agents e.g. heat and trauma * Chemicals * Tissue necrosis – elicits inflammatory reaction

Question 2

What is the purpose of acute inflammation?

Answer 2

To limit disease process

Question 3

Give the five symptom of acute inflammation

Answer 3

• Rubor – redness * Tumor – swelling * Calor – heat * Dolor – pain * Loss of sensation

Question 4

Give four microscopic features of acute inflammation

Answer 4

Tissue oedema Neturophil margination and emigrationDead myocytesNeutrophils

Question 5

What is the purpose of oedema? (3)

Answer 5

Delivers plasma proteins to site of injuryDilutes toxinsIncreases lymphatic drainage

Question 6

Give three plasma proteins involved in oedema

Answer 6

Immunoglobulins, inflammatroy mediators, fibrinogen

Question 7

What is the purpose of vasodilation?

Answer 7

Increases delivery and temperature

Question 8

What is the purpose of neutrophil margination and emigration into site of inflammation?

Answer 8

Removes pathogenic organisms and necrotic debris

Question 9

Explain how rubor relates to microscopic changes

Answer 9

Vasodilation

Question 10

How is tumour caused?

Answer 10

Oedema/infiltration of neutrophils

Question 11

How is calor caused?

Answer 11

Vasodilation

Question 12

How is dolor caused?

Answer 12

• Dolor – result of chemical mediators e.g. bradykinin is also involved in the pain mechanism > dolor enforces rest > reduces chance of further traumatic damage