deck_17621 Flashcards
- A 54-year-old man was in excellent health until 1 month prior hospital admission when he developed acute severe neck pain after bending over to pick up a newspaper. He went to the emergency room where plain x-rays showed only mild arthritic changes. Over the next 4 weeks he saw multiple physicians from different fields and had various therapies including rest, analgesics, and physical therapy, without relief. One week prior to admission he noticed the gradual onset weakness of both upper extremities as well as slowly progressive involuntary neck flexion. At this point, a bone scan revealed increased uptake of the fourth, fifth, and sixth cervical vertebrae. Magnetic resonance imaging demonstrated severe cord compression at the midcervical level. Physical examination at the time of admission indicated a middle-aged man who was ambulatory with a spastic gait. His neck was held in complete flexion and he was unable to extend it. He was afebrile with stable vital signs. There was marked tenderness of the midcervical spine. Neurologic examination demonstrated pronounced weakness with 0/5 strength inthe biceps and 1/5 strength in the deltoids bilaterally. Lower extremity examination showed minimal weakness and increased tone. Upper extremity reflexes were diminished bilaterally; the lower extremities had significant hyper-reflexia with sustained clonus. Toes were upgoing. Sensation was intact and rectal tone was normal. Lab data showed a moderately elevated white blood cell count with a normal differential. Chest xray was normal and lateral cervical spine x-rays demonstrated complete collapse of the fourth and fifth cervical vertebrae, with angulation at that level. The MOST likely diagnosis is: A. pyogenic vertebral osteomyelitis B. metastatic prostate cancer C. epidural hematoma D. nasopharyngeal carcinoma with contiguous spread E. osteoblastama
A. pyogenic vertebral osteomyelitis
- A 54-year-old man was in excellent health until 1 month prior hospital admission when he developed acute severe neck pain after bending over to pick up a newspaper. He went to the emergency room where plain x-rays showed only mild arthritic changes. Over the next 4 weeks he saw multiple physicians from different fields and had various therapies including rest, analgesics, and physical therapy, without relief. One week prior to admission he noticed the gradual onset weakness of both upper extremities as well as slowly progressive involuntary neck flexion. At this point, a bone scan revealed increased uptake of the fourth, fifth, and sixth cervical vertebrae. Magnetic resonance imaging demonstrated severe cord compression at the midcervical level. Physical examination at the time of admission indicated a middle-aged man who was ambulatory with a spastic gait. His neck was held in complete flexion and he was unable to extend it. He was afebrile with stable vital signs. There was marked tenderness of the midcervical spine. Neurologic examination demonstrated pronounced weakness with 0/5 strength inthe biceps and 1/5 strength in the deltoids bilaterally. Lower extremity examination showed minimal weakness and increased tone. Upper extremity reflexes were diminished bilaterally; the lower extremities had significant hyper-reflexia with sustained clonus. Toes were upgoing. Sensation was intact and rectal tone was normal. Lab data showed a moderately elevated white blood cell count with a normal differential. Chest xray was normal and lateral cervical spine x-rays demonstrated complete collapse of the fourth and fifth cervical vertebrae, with angulation at that level. The MOST likely diagnosis is:81. The BEST initial therapy for the patient described in question 80 would be: A. Gardner-Wells tongs followed by a computed tomography-guided biopsy B. Gardner-Wells tongs followed by elective surgery C. immediate operative decompression with methylmethacrylate reconstruction D. immediate operative decompression with autologous bone reconstruction E. high-dose methylprednisolone and radiation therapy
D. immediate operative decompression with autologous bone reconstruction
- In degenerative lumbar spondylosis, stenosis of the lateral recess is most to be caused by: A. the inferior medial aspect of the inferior facet of the vertebral body above the disc B. hypertrophied ligamentum flavum C. a deficient pars interarticularis D. the superior medial aspect of the superior facet of the vertebral body below the disc E. a laterally bulging intervertebral disc
D. the superior medial aspect of the superior facet of the vertebral body below the disc
- A 12-year-old boy presented with a history of generalized headache and a 3-month history of episodic unresponsiveness. The episodes were often preceded by a sense of anxiety and lasted several minutes each. His neurologic examination was normal. The magnetic resonance image shown in Figure 84A was obtained. Which of the following statements is TRUE? A. Cyst peritoneal shunting is not an acceptable treatment. B. The primary abnormality is failure of the temporal lobe to develop. C. The most likely diagnosis is arachnoid cyst. D. Craniotomy for complete removal of the mass and epileptic focus is indicated. E. The most likely diagnosis is epidermoid tumor.
C. The most likely diagnosis is arachnoid cyst.
- A 25-year-old man presents with interscapular pain, hypalgesia below T6 and a spastic paraparesis that has progressed in severity for 1.5 years. The magnetic resonance image shown in Figure 85 was obtained. Which of the following treatments is indicated? A. biopsy and chemotherapy if high-grade astrocytoma is found B. syrinx to pleural shunt C. gross removal ependymoma or low-grade glioma is found D. gross removal and radiation if ependymoma is found E. empiric radiation
C. gross removal ependymoma or low-grade glioma is found
- A 54-year-old man with chronic hypertension requiring medication presents with a 6-year history of involuntary twitching on the left side of his face and a 2-month history of left facial pain. The facial movements had evolved from twitching of the palpebral part orbicularis oculi into spasmodic contractions of most of the muscles about the left eye and cheek. His facial pain is lancinating in nature, precipitated by touching a trigger zone in the orbital temporal region, and radiating superolaterally from above his left eye in the distribution of the supraorbital nerve. Except for mild weakness of the facialmuscles, his neurologic exam is normal. A magnetic resonance image is obtained (seeFigure 86). Which of the following statements is TRUE? A. Tic convulsive may antecede more extensive facial dystonias B. Endovascular treatment may improve the patient’s symptoms. C. An attempt at microvascular decompression is contraindicated D. A trial of carbamazepine is warranted. E. The mass is best approached by a transoral transclival route.
D. A trial of carbamazepine is warranted.
- A 54-year-old man with severe rheumatoid arthritis presents with a 1-week history of progressively increasing midthoracic back pain. He also complains of occasional paresthesia in both anterior thighs with ambulation. His only medication is prednisone, 10 mg/day, which has been taking for 15 years. Examination reveals pain to percussion over the spinous processes of T5-9, associated with paraspinal spasm in the same distribution. Neurologic exam is completely normal, including rectal tone and perianal sensation. Plain radiographs show osteoporosis with compression fractures at T6 and T8 and approximately 30%loss of vertebral body height at both levels. A computed tomographic is obtained and shows an extradural mass extending from T4-10. There is anterior displacement of the spinal cord. Attenuation numbers of the mass suggest fat. The most appropriate and treatment would be: A. blood, urine, and sputum cultures followed by emergent thoracic laminectomy and initiation of broad spectrum antibiotics B. magnetic resonance imaging with gadolinium enhancement, pancultures, urgent thoracic larninectomy,and broad spectrum antibiotics C. Thoracolumbar sacral orthosis bracing, short-term increase in prednisone dosage for cord compression D. MRI with gadolinium,tapering dose of steroids, and rheumatology consult E. urgent thoracic vertebrectomy T6-8 with sturt grafting followed by thoracic laminectomy with spinal instrumentation
D. MRI with gadolinium,tapering dose of steroids, and rheumatology consult
- A 62-year-old man with a 3-month history of progressive spastic cervical myelopathy had a metrizamide computed tomographic scan (Figure 83). All scan slices from C3-5, have the same appearance. Which the following statements is TRUE ?A. The tumor is most likely an osteochondroma B. A chest CT scan is indicated to rule out metastatic spread C. Postoperative radiation, but not chemotherapy, is indicated D. Multilevel medial corpectomy and interbody fusion are indicated E. Calcification of an extrude disc fragment is seen.
D. Multilevel medial corpectomy and interbody fusion are indicated
- Hand-Schuller-Christian disease There are myriad etiologies of lesions in the pediatric and young adult population. Match each disease or lesion in questions 88-92, with the most appropriate clinical, pathologic, or radiographic feature listed in A-E. Some answers may be used more than once: A. colonic polyposis, epidermal inclusion cysts B. “pearlyt” cysts C. Birbeck granule D. radiating spicules of bone E. midline predisposition
C. Birbeck granule
- osteomas There are myriad etiologies of lesions in the pediatric and young adult population. Match each disease or lesion in questions 88-92, with the most appropriate clinical, pathologic, or radiographic feature listed in A-E. Some answers may be used more than once: A. colonic polyposis, epidermal inclusion cysts B. “pearlyt” cysts C. Birbeck granule D. radiating spicules of bone E. midline predisposition
A. colonic polyposis, epidermal inclusion cysts
- Metastatic neuroblastoma There are myriad etiologies of lesions in the pediatric and young adult population. Match each disease or lesion in questions 88-92, with the most appropriate clinical, pathologic, or radiographic feature listed in A-E. Some answers may be used more than once: A. colonic polyposis, epidermal inclusion cysts B. “pearlyt” cysts C. Birbeck granule D. radiating spicules of bone E. midline predisposition
D. radiating spicules of bone
- Hemangioma There are myriad etiologies of lesions in the pediatric and young adult population. Match each disease or lesion in questions 88-92, with the most appropriate clinical, pathologic, or radiographic feature listed in A-E. Some answers may be used more than once: A. colonic polyposis, epidermal inclusion cysts B. “pearlyt” cysts C. Birbeck granule D. radiating spicules of bone E. midline predisposition
D. radiating spicules of bone
- Epidermoid There are myriad etiologies of lesions in the pediatric and young adult population. Match each disease or lesion in questions 88-92, with the most appropriate clinical, pathologic, or radiographic feature listed in A-E. Some answers may be used more than once: A. colonic polyposis, epidermal inclusion cysts B. “pearlyt” cysts C. Birbeck granule D. radiating spicules of bone E. midline predisposition
B. “pearlyt” cysts
- A 60-year-old woman with non-Hodgkin lymphoma is diagnosed as having lymphomatous meningitis following a lumbar puncture. Which of the following are associated with this complication of her disease? a. L5 radiculopathy b. focal seizures, ataxia c. facial nerve palsy d. decreased CSF levels of B-2 microglobulin\
a. L5 radiculopathy b. focal seizures, ataxiac. facial nerve palsy
- Which of the following statements regarding brain stem auditory evoked potentials(BAEPs) are TRUE (Figure 94 A) ? a. Waves I and II generated in the vestibulocochlear (VIII) nerve. b. Signal averaging computers must be used to detect this signal. c. BAEPs are useful in preventing deafness as a complication of posterior fossa surgery. d. BAEPs are very resistant to general anesthesia
a. Waves I and II generated in the vestibulocochlear (VIII) nerve. b. Signal averaging computers must be used to detect this signal. c. BAEPs are useful in preventing deafness as a complication of posterior fossa surgery. d. BAEPs are very resistant to general anesthesia
- Which of the following statements regarding Creutzfeldt-Jakob disease are m e ? a. It is rapidly progressive and death usually occurs within year of onset. b. The recognition of spongiform degeneration is central to the pathologic process.c. Distinct changes in the EEG sharacterize the diseased. The agent responsible for transmission can be inactivated by autoclaving or formalin fixation.
a. It is rapidly progressive and death usually occurs within year of onset. b. The recognition of spongiform degeneration is central to the pathologic process. c. Distinct changes in the EEG