DECK 3 - Central Nervous System drugs

Question 1

SYNAPTIC TRANSMISSION

Answer 1

The process by which one neuron communicates with another neuron. Information is transmitted to the axons of neurons as electrical impulses known as action potentials.

Question 2

It is an age-related degenerative brain disease that means that parts of the brain deteriorate.

Answer 2

Parkinson’s Disease

Question 3

These motions are highly frequent and can occur in any muscle in the body.

Answer 3

MUSCLE SPASM

Question 4

DOXAPRAM

Answer 4

increases in breathing depth and rate. Both post-anesthetic respiratory depression and drug-induced respiratory depression are treated with it.

Question 5

DOPAMINERGIC DRUGS

Answer 5

medicines that, when dopamine levels are low, mimic the effects of dopamine. These drugs work by deceiving the brain into believing that dopamine is present, therefore alleviating condition-related symptoms.

Question 6

ANTICHOLINERGIC AGENT

Answer 6

substances that inhibit or prevent acetylcholine’s effects on the central nervous system, glands, and smooth muscle cells via its parasympathetic nervous system receptors.

Question 7

may cause the release of norepinephrine, a hormone that raises blood pressure and heart rate, from nerve cells.

Answer 7

TYRAMINE REACTION

Question 8

GABAPENTIN

Answer 8

to treat some neurological diseases’ discomfort and avoid seizures. It is not utilized to treat common pain brought on by little accidents or arthritis.

Question 9

to be able to react to stimuli and create an action potential.

Answer 9

NEURONS

Question 10

Sleep disorders

Answer 10

Uses of TEMAZEPAM

Question 11

Drug interactions of GABAa drugs?

Answer 11

When combined with other CNS depressants such as beta-blockers, opiates, and antihistaminics, respiratory depression can become fatal; barbiturates also speed up the metabolism of lipid-soluble medications (oral contraceptives, carbamazepine, phenytoin, warfarin)

Question 12

Valproic acid MOA

Answer 12

Presynaptic Ca+ channels are blocked, GABA transaminase is inhibited, and fast Na channels in axons are inhibited, which reduces conduction and stops seizure propagation.

Question 13

It is recommended for use in conditions such as spinal cord injury, stroke, cerebral palsy, and multiple sclerosis, which are persistent and characterized by skeletal muscular spasticity.

Answer 13

DANTROLENE SODIUM

Question 14

Progressive paralysis, reversible with AChE inhibitors, and no impact on the heart or central nervous system.

Answer 14

Non-depolarizing muscle relaxant properties

Question 15

Symptoms of opiod withdrawal

Answer 15

Anxiety, yawning, lacrimation, rhinorrhea, salivation, muscular spasms, and discomfort with a CNS source. Script: methadone

Question 16

Levodopa, tolcapone, selegiline, bromocriptine, benztropine, amantadine

Answer 16

used in Parkinson disease

Question 17

Contraindications of opiod analgesics

Answer 17

Head traumas, respiratory issues, hepatic or renal issues, thyroid or adrenal deficits, and pregnancy.

Question 18

Properties of succinylcholine

Answer 18

Nicotinic agonist, depolarizing muscle relaxant; Phase I: depolarization, fasciculation, flaccid paralysis; Phase II: desensitization. Caution with malignant hyperthermia, hyperkalemia, and atypical pseudocholinesterase

Question 19

a first-generation anti-convulsant that effectively treats status epilepticus, complex partial seizures, and tonic-clonic seizures without seriously affecting neurological function.

Answer 19

Mechanism action of Phenytoin.

Question 19

PHENYTOIN SIDE EFFECTS

Answer 19

Aplastic anemia, megaloblastic anemia (which reduces folate), hirsutism, osteomalacia (which decreases vitamin D), CNS depression, and teratogenic (cleft lip and palate).