Deck 2 - Antibiotic Drugs Flashcards
Also known as prokaryotes which are
single-celled organisms that lack a true
nucleus and nuclear membrane
BACTERIA
Hans Christian Gram devised a
method to classify bacteria using what
type of method
Gram-stain method
discovered the mold that
produced Penicillin which was the first
antibiotic to be used and marketed
Alexander Fleming
It inhibits bacteria or delays growth.
Bacteriostatic
It kills and remove bacteria.
Bactericidal
minimum amount of antibacterial drug to halt the
growth of microorganisms
MEC or Minimum Effective Concentration
Type of resistance that occurs
without previous exposure to the drug.
Inherent Resistance
Type of resistance caused by prior exposure to
the antibacterial.
Acquired Resistance
Antibiotic combination that is equal to the sum of the effects of two antibiotics.
Additive Effect
Antibiotic combination that – occurs when one antibiotic increases the effectiveness of the 2nd drugs.
Potentiative Effect
when two drugs are used together, the desired effect
may be greatly reduced
Antagonistic Effect
primarily effective against one type of
organism (selective)
NARROW SPECTRUM
effective against gram-positive and gram-negative organisms.
BROAD SPECTRUM
when a drug selected is known to
be the best drug that can kill the Microorganisms.
EMPIRIC THERAPY
once the microorganism is identified in the
lab, the antibiotic therapy is tailored by using the most
narrow-spectrum, least toxic drug based on C&S results
DEFINITIVE THERAPY