Cardiovascular Drugs Flashcards
determined by:
1) myocardial contractility (force with which the ventricles contract)
2) cardiac afterload
3) cardiac preload
STROKE VOLUME
amount of tension (stretch) applied to a muscle before
contraction = force of venous return
PRELOAD
load against which a muscle exerts its force = arterial
pressure that the left ventricle overcomes to eject blood
AFTERLOAD
Defined as a persistent systolic pressure of
greater than 140mmHg and/or a diastolic pressure
of greater than 90mmHg
HYPERTENSION
Determined by the product of cardiac output
and systemic vascular resistance
BLOOD PRESSURE
amount of blood ejected from the left
ventricle and measured in Lpm
CARDIAC OUTPUT
Drugs that accelerate the rate of urine formation
that results to the removal of sodium and
water from the body
DIURETICS
Mechanism of Action: Works along the carbonic anhydrase enzyme system
in the proximal convoluted tubule Carbonic Anhydrase is
needed to make hydrogen ions for the exchange of sodium and water.
ACETAZOLAMIDE
Drug of choice for preventing kidney damage
during acute kidney injury and reduction
of intracranial pressure and cerebral edema.
MANNITOL
An adrenergic drug that acts on the brain by decreasing NE production. Drugs under it is clonidine and methyldopa.
CENTRAL ACTING
A type of angina that is intense but subsides within 15 mins of rest or medication and caused mainly by atherosclerosis and can be triggered by exertion or stress (cold, emotions) and exacerbated by smoking, alcohol, coffee and some drugs.
CHRONIC STABLE ANGINA
A type of angina which is early stage of progressive artery disease characterized by pain increasing in severity and frequency and may even occur at rest.
UNSTABLE ANGINA
A type of angina from spasms of the smooth muscle that surrounds the coronary
arteries and occurs at rest without any triggers but usually occurring at the same time of day.
VASOSPASTIC ANGINA
Pathologic state in which the heart is unable to pump in sufficient amounts
from the ventricles to meet metabolic needs.
HEART FAILURE
Any deviation from the normal rhythm of the heart.
DYSRHYTHMIAS