Deck 1

Question 1

Methylation of _____ can happen in eukaryotic DNA at the 5’ position is permanent and can lead to repression of transcription of underlying DNA, silencing a gene.

Answer 1

Cytosine. This only happens on Cytosines that have Guanines next to them. (CpG)

Question 2

Methylation of _____ can happen in prokaryotic DNA which helps DNA repair enzymes to identify older DNA strands which are used as a reference for repairing damage during DNA replication

Answer 2

Adenine

Question 3

______ can occur by chemical exposure (such as to nitrous acid). This can lead to mutations such as a cytosine turning into a thymine. So what used to be a C-G would turn into a T-G. Proof reading wouldn’t know if the T was the mistake or G so there would be a 50% chance that it would be corrected into the wrong thing.

Answer 3

Deamination of bases