Cards from Practice Exam Flashcards
What is the function of Aminoacyl tRNA synthetases?
To put the correct amino acid on the correct tRNA
During translation, the mRNA is decoded by what process?
The anticodon loop of a cognate tRNA pairs with the 3 nucleotide codon in mRNA.
True of False: Translocation requires ATP hydrolysis.
False
True or False: Peptide bond formation results in the transfer of the growing peptide chain from the P-site tRNA to the
A-site tRNA.
True
True or False: Homologous recombination depends on the availability of the sister chromatid
True
True or False: Homologous recombination initiates with recognition of the double-strand break by Ku
False
True or False: Homologous recombination never leads to genetic exchange between the two chromosomes undergoing the homologous recombination
False
True or False: Homologous recombination can cause loss of heterozygosity
True
True or False: Homologous recombination occurs only in the G1 phase of the cell cycle
False
True or False: During NORMAL double-strand break repair, the repaired sequence is indistinguishable from the sequence prior to the break if homologous
recombination is used.
True
True or False: During NORMAL double-strand break repair, the reading frame does not change if NHEJ is used to repair a break within a protein coding sequence.
False
The decision to use NHEJ instead of homologous recombination to repair DNA Double-Strand Breaks depends on:
Blocking resection of DNA ends, activity of ligase IV, time in the cell cycle
True or False: MicroRNAs (miRNA) play a key role in translational repression
True
True or False: MicroRNAs (miRNA) play a key role in viral RNA degradation
False
True or False: MicroRNAs (miRNA) play a key role in RNA interference
False