Cards from Practice Exam Flashcards

1
Q

What is the function of Aminoacyl tRNA synthetases?

A

To put the correct amino acid on the correct tRNA

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2
Q

During translation, the mRNA is decoded by what process?

A

The anticodon loop of a cognate tRNA pairs with the 3 nucleotide codon in mRNA.

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3
Q

True of False: Translocation requires ATP hydrolysis.

A

False

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4
Q

True or False: Peptide bond formation results in the transfer of the growing peptide chain from the P-site tRNA to the
A-site tRNA.

A

True

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5
Q

True or False: Homologous recombination depends on the availability of the sister chromatid

A

True

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6
Q

True or False: Homologous recombination initiates with recognition of the double-strand break by Ku

A

False

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7
Q

True or False: Homologous recombination never leads to genetic exchange between the two chromosomes undergoing the homologous recombination

A

False

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8
Q

True or False: Homologous recombination can cause loss of heterozygosity

A

True

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9
Q

True or False: Homologous recombination occurs only in the G1 phase of the cell cycle

A

False

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10
Q

True or False: During NORMAL double-strand break repair, the repaired sequence is indistinguishable from the sequence prior to the break if homologous
recombination is used.

A

True

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11
Q

True or False: During NORMAL double-strand break repair, the reading frame does not change if NHEJ is used to repair a break within a protein coding sequence.

A

False

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12
Q

The decision to use NHEJ instead of homologous recombination to repair DNA Double-Strand Breaks depends on:

A

Blocking resection of DNA ends, activity of ligase IV, time in the cell cycle

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13
Q

True or False: MicroRNAs (miRNA) play a key role in translational repression

A

True

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14
Q

True or False: MicroRNAs (miRNA) play a key role in viral RNA degradation

A

False

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15
Q

True or False: MicroRNAs (miRNA) play a key role in RNA interference

A

False

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