Day 8 slides Flashcards

1
Q

descriptive statistics refers to the what?

A

the population

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2
Q

inferential statistics refers to what?

A

the sample

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3
Q

what things does inferential statistics include?

A

CI, p-value, hypothesis testing

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4
Q

What can you inferential stats allow you to do?

A

infer things about larger population from the sample

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5
Q

P-value of less than what is statistically significant?

A

less than 0.05

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6
Q

a smaller standard deviation means what?

A

more certainty

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7
Q

what things should you consider when trying to consider if a study is significant?

A
  • larger difference between means
  • smaller SD= more certainty
  • appropriate sample size
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8
Q

what are confidence intervals?

A

how accurate this estimate is for the whole population

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9
Q

what type of data are CI’s used for?

A

interval or ratio

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10
Q

how do you increase CI?

A
  • increase sample size
  • narrow the variance
  • reduce random measurement errors
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11
Q

Why does increasing sample size help?

A

a bigger sample gives us more confidence in the result and that it can be applied to a larger population

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12
Q

What does it mean to narrow the variance?

A

more homogenous sample risks limiting generalizability

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13
Q

What does a CI actually tell us?

A

confidence intervals tell us what our best guess is for the size of the population effect, 95% of the time

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14
Q

What does a p-value of 0.05 actually mean?

A

it means that the result could have occurred by chance less than 5% of the time, therefore it is likely due to some relationship

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15
Q

What is a t-test?

A

compare two means (significant difference)

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16
Q

What is an independent samples t-test?

A

comparing two different things

17
Q

What is a paired samples t-test?

A

pre-test/post-test; before and after comparing the same thing

18
Q

What is a one-tail approach?

A

there is no real risk for harm, so you only have space to gain; will be seen in a positive distribution

-all 5% is improvement

19
Q

What is the two-tailed approach?

A

2.5% in either direction (may be harmful or helpful)

20
Q

When must you determine if you are doing a one tailed or two tailed approach?

A

must be determined in advance before doing the test

21
Q

what does POEM stand for?

A

patient-oriented evidence matters

22
Q

What is patient-oriented evidence?

A

deals with outcomes of importance to patients, such as changes in morbidity, mortality, or QOL

23
Q

What does DOE stand for?

A

disease oriented evidence

24
Q

What is disease oriented evidence?

A

deals with surrogate and points, such as changes in laboratory values or other measure of response

25
Why is DOE alone not good?
key clinical recommendations lack support of outcomes evidence; doesn't give you the full picture
26
Clinical trials, especially RCTS, have what?
high internal validity, which means you have the ability to determine cause-effect relationships
27
Why do clinical trials have high internal validity?
because you can control for most sources bias, randomization, blinding, and allocation concealment
28
What are explanatory trials?
aims to test whether an intervention works under optimal situations
29
What are the issues with explanatory trials?
- systematic lack of comparative trials in health science literature - can fail to be broadly generalizable
30
What are pragmatic trials?
designed to evaluate the effectiveness of interventions in real-life routine practice conditions
31
What is the problem with pragmatic trials?
susceptible to bias
32
What is good about pragmatic trials?
may produce results that can be generalized and applied in routine practice settings
33
What do critical appraisal tools do?
can be used as a resource to help digest research