Day 3 - Ox. Phos. Flashcards
The inner membrane is impermeable to small molecules, except for which 4 molecules?
O2, CO2, H2O, NH3
The outer membrane is permeable or impermeable to small molecules?
permeable
Intermembrane space pH vs. matrix pH
Matrix pH = High pH Intermembrane Space = low pH
What important processes occur in the matrix?
TCA cycle, Beta oxidation of fatty acids, parts of Urea cycle, pyruvate dehydrogenase activity, and storage of Ca2+ ions.
Correlation Box -Ferredoxins - do what?
carry electrons in p-450 systems of mitochondria. Family members transfer electrons between each other by oxidation and reduction of Fe.
Correlation Box - Cytochrome-c and apoptosis -
Cytochrome-c carries electrons between complexes III & IV. Cytochrome -c can be released from membrane, leads to caspase activation ( = executioners of apoptosis)
Correlation Box - Respiratory chain components encoded by mtDNA
mtDNA replicates independently