David noakes lecture Flashcards
What are the 4 broad categories of subfertility?
Structural
Functional
Management
Infectious
How often should a normal cow cycle
q18-24 days unless pregnant or within 4-6 weeks post partum
5 reasons for no observed oestrus?
freemartinism acylical/anestrus ovarian cysts silent heat not detected
What would you feel on rectal in an acyclical cow?
small flat ovaries, involuted tract
Causes of acyclicity
poor BCS, NEB, concurrent disease, high milk yield
How does low nutrition affect fertility?
Low IGF1 –> reduced response to oestradil & reduced production of GnRH, reduced response to GnRH & reduced FSH and LH, decreased ambryo growth & IFN tao production
What hormonal treatment could you give to an anestrus cow?
PRID or CIDR alone or with GnRH or eCG.
Need to correct nutrition etc as well
What does a normal follicle look like?
1.5-2cm diameter, thin walled, transient.
What does a vacuolated CL look like?
Same size as normal CL, fluid bit in it, identifiable ovulation point. Normal
What does a luteinised follicle look like?
<2.5cm, no sign of ovulation, large cavity. Occur early post partum
What does a follicular cyst look like?
thin walled (<3mm), >2.5cm diameter, fluid filled structure.
What does a luteal cyst look like?
thick walled (>3mm), fluid filled structure >2.5cm diameter. Produce P4.
What is the definition of a cyst?
> 2.5cm, lasts >10 days. Develop from anovulatory graafian follicle.
Which kind of cyst can result in nymphomania?
Follicular cyst (may secrete estrogen)
Why do cysts occur?
hypothalamic level: failure of LH surge (attenuated after calving). Hypothalamus less sensitive to oestradiol after calving.
Ovarian: reduced LH receptors in granulosa cells.
NEB –> NEFAs –> impaired follicular proliferation