Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacy > Data Interpretation > Flashcards

Data Interpretation Flashcards

1
Q

Give 2 key drugs that are either contraindicated or should be used with caution is asthmatics

A

b blockers and NSAIDS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What type of drug is clozapine and give 3 ADRs to be aware of

A

AGRANULOCYTOSIS AND NEUTROPENIA!!!
weight gain
hyperprolactinaemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Give the causes of hyponatramia

A

Hypovolemic - fluid loss via D&V, addisons, diuretics

Euvolemic - SIADH, primary polydipsia, hypothyroid

Hypervolemic - HF, renal failure, liver failure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Give the causes of hypernatraemia

A

Dehydration, drips such as too much IV saline, drugs, diabetes insipidus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Give the main causes of microcytic anaemia

A

TAILS
thalassaemia
anaemia of chronic disease
iron deficiency
lead poisoning
sideroblastic anaemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Give the main causes of a normocytic anaemia

A

Causes: 3A’s and 2H’s
Acute blood loss
Anaemia of chronic disease
Aplastic anaemia

Haemolytic anemia
Hypothyroidism

also chronic renal failure !!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Give the main causes for a macrocytic anaemia

A

Megaloblastic:
B12 deficiency
Folate deficiency

Normoblastic:
Alcohol
Reticulocytosis
Hypothyroidism
Liver disease
Drugs such as azathioprine

myeloproliferative, myelodysplastic and multiple myeloma!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Give causes for high neutrophils (neutrophilia)

A

BACTERIAL INFECTION

tissue damage due to inflammation, infarct or malignancy
Steroid use

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Give reasons for low neutrophils (neutropenia)

A

viral infection, clozapine use, carbimazole, chemo or radiotherapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Give reasons for lymphocytosis

A

VIRAL INFECTION

lymphoma, CLL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Give some causes of thrombocytosis and thrombocytopenia

A

Thrombocytosis - bleeding, tissue damage, post splenectomy, myeloproliferative disorder

Thrombocytopenia - viral illness, penicilliamine!!!, other drugs,.

Heparin, hypersplnism, DIC, ITP HUS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Give causes of SIADH

A

Small cell lung ca
Infection
Abcess
Drugs - carbamepazine and antipsychotics
Head injury

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Give some causes of hypokalaemia

A

Drugs such as loop and thiazide diuretics
Inadequate intake/ intestinal loss via d&/v
Renal tubular acidosis
Endocrine - cushings or conns

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Give some causes of hyperkalaemia

A

Drugs such as potassium sparing diuretics
Renal failure
Addisons
DKA
Rhabdo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

List some nephrotoxic abx and other drugs that cause AKI

A

gentamicin, vancomycin and tetracyclines
NSAIDs ACEin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Give causes of hepatitis including drugs

A

Alcohol, viruses - EBV, Hep, CMV
Drugs - paracetamol OD, rifampicin, statins

17
Q

Define the meaning of narrow therapeutic index

A

small difference in blood concentration of drug between toxic and therapeutic levels

18
Q

List some drugs that cause cholestasis

A

co-amoxiclav, flucloxacillin, nitrofuratoin, steroids, sulfynoreas

19
Q

List some drugs with a narrow therapeutic index

A

digoxin, theophylline, lithium, phenyotin, gentamicin, vancomycin

20
Q

Give the signs of digoxin toxicity

A

Confusion, nausea, visual halos and arryhtmia

21
Q

Give signs of lithium toxicity

A

tremor, tiredness, arrythmia, seizure, coma, renal failure, diabetes insipidus

22
Q

Give signs of phenytoin toxicity

A

gum hypertrophy, ataxia, nystagmus, peripheral neuropathy and teratogenicity

23
Q

Give signs of toxicity for gentalmycin

A

ototoxicity and nepthrotoxocityG

24
Q

Give signs of vancomycin

A

Nephro and ototoxicity

25
Q

If the peak of a drug (when monitoring) is out of range, how should you adjust the drug regime?

A

Adjust the dose

26
Q

If the trough of a drug is out of range, how should you alter the drug regime

A

Adjust the Time you give the dose, i.e dose interval.

Dose stays the same. Wrong Trough, change Time! <3

27
Q

What information is needed to calculate the dose of gentamicin?

A

weight and RENAL FUNCTION!

28
Q

If plot on nomogram falls within 24h area what should be done with drug dosing

A

continue same dose

29
Q

If plot on nomogram falls in 36h area how should the drug regime be changed

A

change to 36 hourly dosing

30
Q

If plot on nomogram falls in 48h area how should the drug regime be changed

A

change to 48 hourly dosing

31
Q
A
31
Q

If plot on monogram falls above 48h area how should the dug regime be changed

A

repeat gent levels and only re dose when conc is under 1mg/L

Pharmacy (10 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions