Dabigatran Drug Information Flashcards
1
Q
What is Dabigatran’s Brand Name?
A
Pradaxa
2
Q
What is Dabigatran’s drug class?
A
ORAL direct thrombin inhibitor
3
Q
What are Dabigatran’s Monitoring parameters?
A
Hemoglobin, Hematocrit, and Serum Creatinine
4
Q
What is Dabigatran’s half life?
A
12-17 hours
5
Q
What disease states are contraindicated for use of Dabigatran?
A
Obesity and Kidney Failure
6
Q
What is the dosing for Dabigatran in Atrial Fibrillation including creatinine clearance ?
A
CrCL >30mL/min: 150mg PO bid
CrCL 15-29mL/min: 75mg PO bid
CrCL <15mL/min: contraindicated
7
Q
What is the dosing for Dabigatran in Venous Thromboembolism including creatinine clearance?
A
CrCL >30mL/min: 5 days parenteral, then 150mg PO bid
CrCL <30mL/min: contraindicated
8
Q
Which has a higher risk of GI bleed: Warfarin or Dabigatran?
A
Dabigatran
