Cytokines (sources + functions) Flashcards
1
Q
IL-1
A
source = macrophages function = acute inflammation, induces fever
2
Q
IL-2
A
source = Th1 cells function = stimulates growth + differentiation of T-cell response
3
Q
IL-3
A
source = activated T-helper cells function = stimulates differentiation + proliferation of myeloid progenitor cells
4
Q
IL-4
A
source = Th2 cells function = stimulate proliferation + differentiation of B-cells
5
Q
IL-5
A
source = Th2 cells function = stimulate production of eosinophils
6
Q
IL-6
A
source = macrophages, Th2 cells function = stimulates differentiation of B-cells, induces fever
7
Q
IL-8
A
source = macrophages function = neutrophil chemotaxis
8
Q
IL-10
A
source = Th2 cells function = Inhibits Th1 cytokine production
9
Q
IL-12
A
source = dendritic cells, macrophages, B-cells function = activates NK cells + stimulates differentiation of naive T-cells into Th1 cells
10
Q
Tumour necrosis factor-alpha
A
source = macrophages function = induces fever, neutrophil chemotaxis
11
Q
Interferon-gamma
A
source = Th1 cells function = activates macrophages
