cytokines (IL and others) Flashcards
found in macrophages
-acute inflammation
-induces fever
IL-1
found in Th1 cells
stimulate growth + differentiation of T cell response
IL-2
found in activated T helper cells
-stimulate differentiation + proliferation of myeloid progenitor cells
IL-3
Found in Th2 cells
stimulates proliferation + differentiation of B cells
IL4
found in macrophages, Th2 cells
-stimulate differentiation of B cells
-induces fever
IL-6
found in macrophages
-involved in neutrophil chemotaxis
IL-8
found in Th2 cells
-inhibit Th1 cytokine production
IL-10 cells
found in dendritic cells, macrophages, B cells
activate NK cells + stimulates differentiation of naive T cells into Th1 cells
IL-12
found in macrophages
-induce fever
tumour necrosis factor -α (not IL)
found in Th1 cells
-activate macrophages
Interferon-y