cytokines Flashcards
1
Q
Neutrophil chemotactic factor
A
IL-8
2
Q
IL-4 redundancy
A
IL-13
3
Q
HIV gp120 antagonist
A
IL-16
4
Q
promote megakaryocyte differentiation
A
IL-11
5
Q
induce RORyt expression
A
IL-23
6
Q
sustain memory CD8+T cell survival
A
IL-15,IL-7
7
Q
induce M1 differentiation
A
IL-2, IFN-y
8
Q
cachexin
A
TNF-a
9
Q
promote Th0 → Th17
A
IL-6, TGF-b
10
Q
promote class switching to IgG2a
A
IFN-y
11
Q
Treg → Th17
A
IL-6,21,23, TGF-β
RORγt(need IL-23) , IRF4 , STAT3
Reference:Th0–> Th17 : IL-6 and TGF-b
12
Q
Th17 → Treg
A
IL-2, RA(retinoicacid), IDO (indoleamine2,3-dioxygenase)
T-bet, FoxP3 , STAT5
13
Q
CD22
A
co-inhibitory molecule of B cell
14
Q
antibodies with extra constant domain
A
IgM / IgE
15
Q
isotype with secretary component
A
IgM / IgA