Cytokines Flashcards

1
Q

Ebi

A

Member of the IL-12 heterodimeric family of cytokines

Structuraly similar to the IL-12b chain

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2
Q

IL-27

A

Heterodimer of Ebi and IL-27a (p28)

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3
Q

IL27a

A

Structurally similar to IL-12a, encoded by il27 also known as p28 Pairs with ebi to make IL-27

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4
Q

Lymphotoxin a/b

A

Members of the TNF family that form homo or heterotrimerd

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5
Q

LTa homotrimer

A

Binds to TNFR1 or 2 with equal affinity

Soluble lymphotoxin

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6
Q

LTa/b heterotrimer

A

This is the membrane bound form of lymphotoxin that binds exclusively to LTbR which is expressed exclusively on nonlymphoid cells

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7
Q

LTab and LTbR in lymphogenesis.

A

Development and function of secondary lymphoid organs

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