Cytokines Flashcards
1
Q
IL-2
A
Secreted by T cells
Stimulates: helper T cells, cytotoxic T cells
2
Q
IL-4
A
Differentiation into TH2 cells,
Stimulates B cells
Class switches to IgG and IgE
3
Q
IL-5
A
Class switch to IgA and eosinophils
4
Q
IL-8
A
Chemotaxis for PMN
5
Q
IL-10
A
Inhibits TH1 and T cells
6
Q
IL-12
A
Differentiates T cells into th1 and activates NK cells
7
Q
TNF-a
A
Septic shock
Increase vascular permeability
8
Q
INF-y
A
Activates NK cells
9
Q
Septic shock
A
IL-1, IL-6 and TNF-a
10
Q
IL-1
A
1st to be released. Fever, secreted by macrophages, acute inflammation, causes secretion of IgA
