cytokines

Question 1

il1 function

Answer 1

lymphocyte activation
leukocyte endothelial adhesion
fever
promotes haematopoiesis

Question 2

il2 function

Answer 2

t cell growth factor

Question 3

il3 function

Answer 3

stimulates bone marrow growth

Question 4

il4 function

Answer 4

b cell growth factor
IgE production
fibroblast proliferation

Question 5

il5 function

Answer 5

B cell growth factor
activation of eosinophils

Question 6

il6 function

Answer 6

b cell differentiation
synthesis of acute phase proteins
synergistic affects with il1 and TNFa

Question 7

il7 function

Answer 7

development of t and b cell pre-cursors

Question 8

il8 function

Answer 8

stimulates the activity of neutrophils as a chemotaxin
inhibitor of endothelial cell leukocyte adhesion

Question 9

il9 function

Answer 9

t cell and mast cell growth factor

Question 10

il10 function

Answer 10

suppresses development of TH1 cells by inhibition of macrophages
IL12 production
inhibits inflammatory and immune responses

Question 11

il11 function

Answer 11

synthesis of acute phase proteins
synergistic effects on haematopoiesis

Question 12

il12 function

Answer 12

enhances B cell expression of IFN-y during t cell activation
stimulates synthesis of NK cells
promotes TH1 cells and suppresses TH2 cells

Question 13

Il13 function

Answer 13

similar to IL4

Question 14

il17 function

Answer 14

promotes t cell proliferation

Question 15

source of il1

Answer 15

macrophages
lymphocytes
endothelium
fibroblasts

Question 16

source of il2

Answer 16

activated t cells

Question 17

source of IL3

Answer 17

t cells

Question 18

source of il4

Answer 18

t cell and mast cells

Question 19

source of il5

Answer 19

activated t cells

Question 20

source of il6

Answer 20

t cells
b cells
macrophages
fibroblasts

Question 21

source of il7

Answer 21

lymphocytes

Question 22

source of il8

Answer 22

t cells
macrophages

Question 23

source of il9

Answer 23

t cells

Question 24

source of il10

Answer 24

t cells
b cells
monocytes

Question 25

source of il11

Answer 25

bone marrow stromal cells

Question 26

source of il12

Answer 26

macrophages

Question 27

source of il13

Answer 27

th2 cells