CVS-Respi [Head and Neck Cancer] Flashcards
All of the following tumors are squamous cell in origin EXCEPT:
A. Paranasal sinuses
B. Oral cavity
C. Oropharynx
D. Larynx
E. None of the options
E. None of the options
All of the following are the most significant environmental risk factors for head and neck cancer EXCEPT:
A. Alcohol
B. Tobacco use
C. EBV / HPV infections
D. None of the options
C. EBV / HPV infections
Nasopharyngeal carcinoma is mostly associated with which of the following?
A. Smokeless tobacco
B. HPV infection
C. EBV infection
D. Low consumption of fruits and vegetables
E. All of the options
C. EBV infection
ALL of the following are TRUE about oropharyngeal cancer EXCEPT:
A. HPV 16 is the dominant viral subtype
B. Associated w/ increased numbers of sexual partners
C. Occurs in older patient population
D. Better prognosis for nonsmokers
E. None of the options
C. Occurs in older patient population
ALL of the following are TRUE about premalignant lesions EXCEPT:
A. Erythroplakia (red patch)
B. Leukoplakia (white patch)
C. Can be classified as hyperplasia and dysplasia only
D. Most patients do not present with a known history of premalignant lesions
E. None of the options
C. Can be classified as hyperplasia and dysplasia only
Hyperplasia, dysplasia, carcinoma in situ, carcinoma
Which of the following screening is RECOMMENDED for lung cancer in heavy smokers who have developed head and neck cancer?
A. Chest XRay
B. CT
C. MRI
D. PET
E. Any of the options
B. CT
Mutations that result to head and neck cancer affect all of the following EXCEPT?
A. Mitotic signaling
B. Genetic stability
C. Cellular proliferation
D. Differentiation
E. None of the options
E. None of the options
All of the following are TRUE about clinical presentation of head and neck cancers EXCEPT:
A. Tobacco-related : >75yrs old
B. HPV-related : 20s to 30s
C. EBV : 40s to 50s
D. None of the options
D. None of the options
Tobacco: >60
HPV: 40s to 50s
EBV: all ages
All of the following manifest in carcinomas of the oral cavity EXCEPT:
A. Nonhealing ulcers
B. Changes in fit of dentures
C. Painless lesions
D. Masses
E. None of the options
C. Painless lesions
Which of the following is frequently noted as first sign of HPV-related tumors?
A. Otitis media
B. Neck lymphadenopathy
C. Hoarseness
D. Fever
E. Any of the options
B. Neck lymphadenopathy
Which of the following procedure is/are needed for definitive staging of the carcinoma?
A. CT
B. MRI
C. PET
D. Endoscopy
E. Two of the options
F. All of the options
D. Endoscopy
According to TNM-AJCC, T1N1M1 belongs to what stage?
A. Stage IVA
B. Stage IVB
C. Stage IVC
D. Stage IVD
C. Stage IVC
Stage IVC - Any T, Any N, M1
Which of the following treatment modality is mostly preferred for laryngeal cancer Stage 1?
A. Radiation therapy
B. Surgery
C. Chemotherapy
D. Radiochemotherapy
E. Any of the options
A. Radiation therapy
More than 50% of the head and neck cancer patients are clinically categorized as:
A. Localized disease
B. Locally or regionally advanced disease
C. Intermediate disease
D. Recurrent and/or metastatic disease
E. Any of the options
B. Locally or regionally advanced disease
All of the following are part of the current standard for induction chemotherapy EXCEPT:
A. Docetaxel
B. Paclitaxel
C. Cisplatin
D. Fluorouracil
E. None of the options
B. Paclitaxel
Which of the following toxicities is increased with concomitant chemoradiotherapy?
A. Xerostomia
B. Nephrotoxicity
C. Mucositis
D. Otitis media
E. All of the options
C. Mucositis
EXTREME regimen involves all of the following EXCEPT:
A. Cisplatin
B. Rituximab
C. Cetuximab
D. Fluorouracil
E. None of the options
B. Rituximab
EXTREME (Cisplatin, 5-FU, Cetuximab)
All of the following are long term complications of radiotherapy EXCEPT:
A. Xerostomia
B. Dysphagia
C. Neck fibrosis
D. Nephrotoxicity
E. None of the options
D. Nephrotoxicity
Which of the following is/are common side effects of Cisplatin?
A. Myelosuppression
B. Nephrotoxicity
C. Ototoxicity
D. Two of the options
E. All of the options
E. All of the options
Which of the following lymph nodes are LAST to be involved in NPC?
A. Anterior triangle
B. Posterior triangle
C. Upper jugular
D. Supraclavicular
E. Any of the options
D. Supraclavicular
First = posterior triangle & upper jugular
Nasopharynx is bounded superiorly by which of the following structures?
A. Skull base
B. Nasal cavity
C. Posterior pharyngeal wall
D. Medial pterygoid plates
E. Superior pharyngeal constrictor muscles
A. Skull base
Boundaries of the nasopharynx:
* Superiorly: the Skull base.
* Anteriorly: the nAsAl cAvity.
* Posteriorly: posterior pharyngeal wall.
* InFeriorly: the soFt palate.
* Laterally: the medial pterygoid plates and superior pharyngeal constrictor muscles
NPC most commonly originates in which of the following?
A. Eustachian tube opening
B. Torus tubarius
C. Fossa of Rossenmuller
D. Adenoids
E. Any of the options
C. Fossa of Rossenmuller
ALL of the following are risk factors linked to NPC EXCEPT:
A. Increased age
B. Regular consumption of salt-cured foods
C. EBV
D. Male sex
E. None of the options
E. None of the options
Which of the following studies remains the modality of choice for bone invasion and extent of some soft tissues?
A. CT
B. MRI
C. PET
D. Endoscopy
E. Any of the options
A. CT
Which imaging study is the superior modality for assessing intracranial extension, cranial nerve involvement, and defining paranasal sinus involvement?
A. CT
B. MRI
C. PET
D. Endoscopy
E. Any of the options
B. MRI
Which of the following is the modality of choice for assessing remission and investigating recurrence
A. CT
B. MRI
C. PET
D. Endoscopy
E. Any of the options
C. PET
According to WHO, Type II NPC is also called as _______?
A. Squamous cell carcinoma
B. Squamous cell carcinoma w/ differentiation
C. Non-keratinizing carcinoma
D. Undifferentiated carcinoma
E. Two of the options
C. Non-keratinizing carcinoma
Which of the following remains the mainstay treatment for locally advanced regional head and neck cancer?
A. Radiotherapy
B. Adjunct Chemotherapy
C. Concomitant chemoradiotherapy
D. Surgery
C. Concomitant chemoradiotherapy
Which of the following remains the management of choice for primary lesions and cervical metastases of NPC?
A. Radiotherapy
B. Chemotherapy
C. Chemoradiotherapy
D. Surgery
A. Radiotherapy
Which of the following is the most common complication of NPC?
A. Otitis media
B. Otitis media w/ effusion
C. Mucositis
D. Xerostomia
E. Any of the options
B. Otitis media w/ effusion