CVS Pharmacology Flashcards

1
Q

Class I anti-arrhythmic? L09

A

V-gated Na+ channel blockers

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2
Q

Class II anti-arrhythmic? L09

A

Beta blockers

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3
Q

Class III anti-arrhythmic? L09

A

K+ channel blockers

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4
Q

Class IV anti-arrhythmic? L09

A

L-type Ca2+ channel blockers

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5
Q

Example of class I anti-arrhythmic? L09

A

Lidocaine

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6
Q

Example of class II anti-arrhythmic? L09

A

Propanolol
Atenolol
Bisoprolol

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7
Q

Example of class III anti-arrhythmic? L09

A

Amiodarone

Dronedarone

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8
Q

Example of class IV anti-arrhythmic? L09

A

Verapamil

Amlodopine

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9
Q

How does adenosine work? L09

A

Opens K+ channels causing hyperpolarisation

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10
Q

How does digoxin work? L09

A

Partly inhibits Na+/K+ ATPase, increasing intracellular Ca2+ concentration. Decreases AV conduction rate, increasing filling time and SV

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11
Q

How do PDE inhibitors work? L09

A

Increase cAMP level, increasing the force of contraction

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12
Q

Example of PDE inhibitor? L09

A

Milirinone

Enoximone

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13
Q

Alpha-1 agonist example? L12

A

Phenylephrine

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14
Q

Alpha-2 agonist example? L12

A

Clonidine

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15
Q

Alpha-1 antagonist example? L12

A

Doxazosin

Prazosin

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16
Q

Beta-1 agonist example? L12

A

Dobutamine

Isoprenaline

17
Q

Beta-2 agonist example? L12

A

Salbutamol

Isoprenaline

18
Q

Beta-1 antagonist example? L12

A

Metoprolol

Carvedilol

19
Q

ACE inhibitor example? L19

A

Lisinopril

20
Q

AT1 receptor antagonist example? L19

A

Losortan