CVS Pharmacology Flashcards
Class I anti-arrhythmic? L09
V-gated Na+ channel blockers
Class II anti-arrhythmic? L09
Beta blockers
Class III anti-arrhythmic? L09
K+ channel blockers
Class IV anti-arrhythmic? L09
L-type Ca2+ channel blockers
Example of class I anti-arrhythmic? L09
Lidocaine
Example of class II anti-arrhythmic? L09
Propanolol
Atenolol
Bisoprolol
Example of class III anti-arrhythmic? L09
Amiodarone
Dronedarone
Example of class IV anti-arrhythmic? L09
Verapamil
Amlodopine
How does adenosine work? L09
Opens K+ channels causing hyperpolarisation
How does digoxin work? L09
Partly inhibits Na+/K+ ATPase, increasing intracellular Ca2+ concentration. Decreases AV conduction rate, increasing filling time and SV
How do PDE inhibitors work? L09
Increase cAMP level, increasing the force of contraction
Example of PDE inhibitor? L09
Milirinone
Enoximone
Alpha-1 agonist example? L12
Phenylephrine
Alpha-2 agonist example? L12
Clonidine
Alpha-1 antagonist example? L12
Doxazosin
Prazosin