CVS 8 Special Circulations Flashcards

1
Q

2 circulations of the lungs

A

Bronchial circulation - meets the metabolic requirements of the lungs
Pulmonary circulation - required for gas exchange

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Cardiac output at rest

A

5L/min

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Maximum cardiac output

A

20-25L/min

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Pressure in right atria

A

0-8mmHg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Pressure in left atria

A

1-10mmHg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Pressure in right ventricle

A

15-30mmHg - systole
0-8mmHg- diastole - same as RA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Pressure in left ventricle

A

100-140mmHg - systole
1-10mmHg - diastole - same as LV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Compare and contrast the features of pulmonary and systemic circulation

A

pulmonary circulation:
- lower pressure + resistance
- short, wide vessels
- many capillaries
- arterioles have little smooth muscle

systemic circulation
- higher pressure + resistance
- larger, narrower vessels
- variable blood flow to capillaries
- arterioles have thick walls

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Adaptations to promote efficient gas exchange

A

High density of capillaries - large surface area
Short diffusion distance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is hypoxic pulmonary vasoconstriction?

A

Occurs when alveoli are not well ventilated
Vasoconstriction of pulmonary vessels
Ensures perfusion matches ventilation
Helps optimise gas exchange

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Consequence of chronic hypoxic vasoconstriction

A

Increases resistance > hypertension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Outline when the vessels of the lungs are open/closed

A
  • apical vessels - collapse during diastole
  • vessels at the level of the heart - constantly open
  • vessels at base of lungs - increased hydrostatic pressure > vessels distended
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Effect of exercise on pulmonary blood flow in lungs

A
  • apical vessels - open due to increase pressure
  • vessel at level of heart - constantly open
  • vessels at base of lungs - increased hydrostatic pressure > vessels distended
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Outline the formation of tissue fluid

A
  • hydrostatic pressure pushes fluid out of capillary
  • oncotic pressure draws fluid into capillary
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

How does the cerebral circulation meet the high demand for oxygen?

A

High capillary density > large surface area
High basal flow rate
Reduced diffusion distance
High O2 extraction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

How is secure cerebral blood supply ensured?

A

structurally:
- circle of Willis
.
functionally:
- myogenic autoregulation maintains perfusion in hypotension
- metabolites control blood flow
- brain stem regulates other circulation

17
Q

What is hyper and hypocapnia?

A

High + low CO2 partial pressure

18
Q

What happens to cerebral vessels in hypercapina and hypocapina?

A

hypercapina - vasodilation
hypocapina - vasoconstriction

19
Q

How does myogenic auto regulation control blood supply?

A

Vasoconstriction if BP increases
Vasodilation if BP decreases

Fails below 50mHg

20
Q

What act as vasodilators?

A

Increased [K+]
Increased osmolarity
Inorganic phosphates
Adenosine
Decreased pH

21
Q

Outline atereovenous anastomoses?

A

In apical skin
Under neural control
Decrease core temperature closes AVAs
Increased core temperature opens AVAs > dilate > blood nearer to suface

22
Q

What is the ventilation-perfusion ratio?
V:Q

A

Ratio between the volume of air coming in and out of lungs and the volume of blood flowing past the lungs in pulmonary circulation

23
Q

What is the optimal V:Q ratio?

A

0.8