CVS 1 Haemodynamics Flashcards
Haemodynamics meaning
Physical factors that control blood flow
What is serum?
Plasma without clotting factors
What is fluid collected from clotted blood called?
Describe the composition after centrifuging
Serum
COMPOSITION
Serum
Clot
What is fluid collected from unclotted blood called?
Describe the composition after centrifuging
Plasma
COMPOSITION
Plasma
Buffy coat - WBCS + platelets
RBCS
What can change whole blood viscosity?
Polycythemia - increased RBC
Thrombocytopenia- increased platelets
Leukaemia- increased WBCs
Causes sludgey thick blood
What can cause min changes to whole blood viscosity?
Acute phase plasma proteins
E.g. fibrinogen, compliment , C reactive protein
What is C reactive protein an indicator of?
Inflammation
Flow meaning and units
Volume of blood transferred per time unit
mL/min
What does total flow equal?
Cardiac output
Pressure meaning and units
Force per unit area
mmHg for blood pressure
How are flow and resistance related?
Reciprocally
Resistance meaning
Measure of difficulty of flow
Types of blood flow
Laminar
Turbulent
Describe laminar flow
Smooth
Silent
Maintains energy
Typical in most vessels
Describe turbulence flow
Disorganised
Noisy
Energy lost
Stenosis meaning
Abnormal discrete narrowing of an artery/open area of heart valve
What can be felt and heard in turbulent flow?
Thrill can be felt
Bruit can be heard