CV Pharmocology Flashcards
What drugs are used in the treatment of CV diseases?
ACE Inhibitors
Beta Blockers
Calcium Antagonist
Diuretic
Describe the sequence of drugs used to treat normal hypertension
- Patients younger that 55 start with an ACEI/ARB and older patients with Calcium Antagonist
- Then C/A
- Then a diuretic
What drugs are used to treat severe hypertension?
Beta or alpha blocker or spironolactone
What drugs are used in all patients with CHF?
DAB
Diuretic to rid the body of fluid retention
ACE Inhibitor and Beta blocker to remodel the heart
If CHF patients are still exhibiting signs like breathlessness after initial drug treatment, what drugs should be used?
Spironolactone and Eplerenone
Who would receive Cardiac synchronisation therapy?
CHF patients with long QRS segments on an ECG where drug treatment has failed
What can be done for patients with severe CHF
implantable cardiac defibrillators
What is sacubitril vasartan?
new dual drug used in severe heart failure that replaces ACEI or ARB
What is used to prolong survival in patients with Angina?
SAAB
Statin, aspirin, ACE inhibitor and beta blocker
What is used to relieve the symptoms of angina
beta blocker
calcium antagonist/nitrates
coronary angioplasty
New antianginals - ivabradine and ranolazine
How can chest pain be classified?
Non cardiac or cardiac
cardiac chest pain can be classified as troponin -ve which is called troponin -ve ACS.
troponin +ve can be classified as a STEMI or non-STEMI
Who might receive fondaparinux?
STEMI patient
synthetic pentasaccharide that inhibits activated factor X
describe the emergency management of STEMI
aspirin with angioplasty or thrombolysis
decribe the similarities in treatment of STEMIs and non-STEMIs
they both receive aspirin and clopidogrel/ticagrelor
they both receive SAABs as prophylaxis
describe the differences in treatment of STEMIs and non-STEMIs
use of angioplasty is selective in non-STEMIs
STEMIs recieve heparin/fondaparinux