CV IV Flashcards
evolution of MI
LAD > RCA > circumflex
0-4 hours - no change
4-24 hour - early coag necrosis - wavy fibers
-reperfusion = contraction bands
3-14 days - free wall rupture
-macros and granulation tissue at margins
2 weeks to several months - scar formation
tamponade
can occur with transmural MI - rupture
also - can get mitral regurg - pap muscle rupture
MI diagnosis
6 hours - EKG gold standard
cardiac troponin I - rises after 4 hours - elevated 7-10 days
CK-MB - rises after 6-12 hours - return to normal 48 hours
-good for diagnosing reinfarction
ST elevation
transmural infarction
Q wave
ST depression
subendothelial infarction
V1-V2 EKG STEMI
anteroseptal
-LAD
V3-4 EKG STEMI
anteroapical
-distal LAD
V5-6 EKG STEMI
anterolateral
-LAD or LCX
I aVL EKG STEMI
lateral
-LCX
II, III, aVF EKG STEMI
inferior
-RCA
MI complication
prehospital - arrhythmia
also - LV failure
dressler syndrome
autoimmune phenomenon - fibrinous pericarditis
several weeks post MI
mitral regurg after MI
papillary muscle rupture
tx unstable angina and NSTEMI
anticoag antiplatelet beta-block ACE I statin sx control - nitro/morphine
MC cardiomyoathy
dilated
dilated cardiomyopathy causes
chronic alcohol coxsackie B cocaine chagas doxorubicin
see HF and S3
hypertrophic cardiomyopathy
familial - auto dominant
-beta-myosin heavy chain mutation
syncope during exercise - young athlete
see S4 and systolic murmur
disarray of fibers
septal hypertrophy
restrictive cardiomyopathy
sarcoid
amyloid
loffler syndrome
eosinphilic infiltrate
diastolic heart failure
decreased compliance
systolic heart failure
decreased contractility
right HF
from left HF
decrease HF mortality
ACE I
ARB
B-blocker
spironolactone
left heart failure
orthopnea
paroxysmal nocturnal dyspnea
pulmonary edema
right heart failure
hepatomegaly - nutmeg liver
JVD
peripheral edema
transudate
no inflammation
exudate
inflammation
distributive shock
warm and dry skin
-with sepsis, CNS injury, and anaphylaxis
obstructive shock
cardiac tamponade
pulmonary embolus
hypovolemic shock
decreased preload
cardiogenic shock
decreased CO
distributive shock
decreased afterload
roth spot
white spot retina - endocarditis
osler node
tender raised lesion finger or toe pad
-endocarditis
janeway lesion
palm and sole
endocarditis
subacute bacterial endocarditis
strep viridans
-on damaged/abnormal valve - gradual onset
acute bacterial endocarditis
staph aureus
-on normal valve - rapid onset
IV drug valve
tricuspid
culture negative bacterial endocarditis
HACEK haemophilus actinobacillus cardiobacterium eikenella kingella
bacterial endocarditis valve
often mitral