CV I Flashcards
defect left right dynein
kartagener
truncus arteriosus
asc aorta and pulm trunk
bulbus cordis
smooth L and R ventricles
prim pulm vein
smooth left atria
left horn sinus venosus
coronary sinus
cardinal vein
SVC
closure foramen ovale
LA pressure
valve is remainder of septum primum
valve embryo
from endocardial cushions
ebstein anomaly
tricuspid leaflet toward apex right ventricle
fetal RBC synthesis
yolk sac - 3-8 weeks
liver - 6 weeks > birth
spleen - 10-28 weeks
bone marrow - 18 weeks > adult
fetal Hb
alpha 2 gamma 2
higher affinity O2 - less avid binding 2,3 BPG
HbA1
adult - alpha 2 beta2
shunts of fetal circulation
ductus venosus - umbilical v to IVC
foramen ovale - Ox blood from placenta > IVC > right hear
- R heart to L heart
- close with first breath
ductus arteriosus - pulmonary a to aorta
close PDA
PGE2 keep open
-close - indomethacin
falciform ligament
umbilical vein
from ligamentum teres hepatis
allantois
urachus
-bladder to umbilicus
median umbilical ligament
SA and AV node blood supply
right coronary a
right dominant
90%
-posterior descending from right coronary a
left dominant
10%
-posterior descending from circumflex of left coronary a
coronary blood flow
early diastole
MC coronary a occulsion
LAD
anterior IV septum, anterolateral pap muscle, anterior surface L ventricle
blood supply right ventricle
right marginal a
blood supply lateral and posterior wall left ventricle
left circumflex
blood supply posterior 1/3 IV septum, posterior walls of ventricles
posterior descending
posterior part of heart
left atrium
-enlargement - dysphagia
fick principle
CO = O2 consume / A - V O2 content
MAP =
CO x TPR = 2/3 diastolic + 1/3 systolic
pulse P
systolic P - diastolic P
increase - aortic regurg
decrease - aortic stenosis / tamponade
digitalis
block Na/K pump - more Na
-less Na/Ca exchange - more Ca in cell
more contraction
laplace law
wall tension = P x radius / 2x wall thickness
hydralazine
vasodilator - arterial
ejection fraction
normal 55% - measure ventricle contraction
hypertrophy
compensate increased afterload
-to decrease wall tension
resistance
proportional - inverse - R~4
multiple myeloma
increased viscosity - increased resistance
capillary
high total cross section
low flow velocity
contractile force
proportal end diastolic length of cardiac muscle fiber
mean systemic pressure
not changed with alteration in TPR
JVP
A C X V Y
A - atrial contraction C - RV contraction - tricuspid bulge X descent - atrial relax V wave - filling right atrium Y descent - RA emptying
S4
late diastole
ventricular hypertrophy
S3
normal children and pregnant women