CV A&P Flashcards

1
Q

cardiac output

A

SV x HR = CO
–amount of blood that the heart pumps out of the left ventricle each minute

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2
Q

CO and HF

A

CO is diminished in HF because the left ventricle is weakened and cannot adequately pump blood out of the chamber

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3
Q

SV is the difference between…

A

volume of blood at the end of relaxation and residual volume of blood remaining in the ventricle after ejection

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4
Q

three major factors influencing SV

A

(1) preload
(2) afterload
(3) myocardial contractility

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5
Q

preload

A

stretch of cardiac muscle cells before contraction

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6
Q

afterload

A

resistance that must be overcome in order to eject blood from the chamber

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7
Q

contractility

A

contractile capabilities of the heart

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8
Q

relationship between preload and SV

A

lower preload = lower SV

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9
Q

Frank-Starling Law

A

an increase in resting muscle fiber length results in greater muscle tension
ex. the heart has the ability to change its force of contraction in response to changes in venous return

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10
Q

hydrostatic pressure

A

a force that attempts to push fluid out of the capillary pores and into the interstitial and intracellular spaces
ex. water pushing pressure

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11
Q

oncotic (osmotic) pressure

A

force that attempts to pull fluid from the interstitial and intracellular spaces into the capillary
ex. water pulling pressure

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12
Q

Starling’s Law of Capillary Forces

A

oncotic pressure forces and hydrostatic pressure forces oppose each other at every capillary membrane and attempt to balance each other out

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13
Q

left ventricular afterload

A

primarily determined by aortic blood pressure

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14
Q

afterload and SV

A

a decrease in afterload will lead to a decrease in SV unless the heart compensates

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15
Q

determination of contractility

A

primarily determined by the amount of free calcium within the myocardial cell

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16
Q

contractility and SV

A

increased contractility increases SV by causing a greater % of the volume to be ejected

17
Q

heart blood flow

A

vena cavae/coronary sinus –> right atrium –> right ventricle –> pulmonary artery –> lungs –> pulmonary veins –> left atrium –> left ventricle –> aorta

18
Q

backward effect of failing left ventricle

A

creates a buildup of hydrostatic pressure in the left atrium, pulmonary veins, and pulmonary capillaries

19
Q

forward failure effects

A

cause decreased perfusion of the brain, kidneys, and other organs

20
Q

example of backward effect in LVF

A

pulmonary edema

21
Q

crackles with mild pulmonary edema

A

fine crackles

22
Q

crackles with severe pulmonary edema

A

coarse, bubble-like

23
Q

sputum with severe pulmonary edema

A

pink, frothy sputum

24
Q

LVF backward effects

A

–dyspnea
–cough
–orthopnea
–paroxysmal nocturnal dyspnea
–crackles in lungs

25
Q

forward effects in LVF definition

A

–cause inadequate ejection of blood into the aorta and diminished perfusion throughout whole arterial circulatory system
–decreased perfusion of vital tissues activates a neurohormonal response that includes stimulation of RAAS, ADH, and SNS

26
Q

adrenergic stimulation of heart

A

increases HR

27
Q

adrenergic stimulation of vasculature

A

vasoconstriction

28
Q

diminished perfusion and posterior pituitary

A

releases ADH, which acts on the nephrons to increase water reabsorption into the bloodstream and, in turn, leads to increased BV