CV A&P Flashcards
cardiac output
SV x HR = CO
–amount of blood that the heart pumps out of the left ventricle each minute
CO and HF
CO is diminished in HF because the left ventricle is weakened and cannot adequately pump blood out of the chamber
SV is the difference between…
volume of blood at the end of relaxation and residual volume of blood remaining in the ventricle after ejection
three major factors influencing SV
(1) preload
(2) afterload
(3) myocardial contractility
preload
stretch of cardiac muscle cells before contraction
afterload
resistance that must be overcome in order to eject blood from the chamber
contractility
contractile capabilities of the heart
relationship between preload and SV
lower preload = lower SV
Frank-Starling Law
an increase in resting muscle fiber length results in greater muscle tension
ex. the heart has the ability to change its force of contraction in response to changes in venous return
hydrostatic pressure
a force that attempts to push fluid out of the capillary pores and into the interstitial and intracellular spaces
ex. water pushing pressure
oncotic (osmotic) pressure
force that attempts to pull fluid from the interstitial and intracellular spaces into the capillary
ex. water pulling pressure
Starling’s Law of Capillary Forces
oncotic pressure forces and hydrostatic pressure forces oppose each other at every capillary membrane and attempt to balance each other out
left ventricular afterload
primarily determined by aortic blood pressure
afterload and SV
a decrease in afterload will lead to a decrease in SV unless the heart compensates
determination of contractility
primarily determined by the amount of free calcium within the myocardial cell